Literature DB >> 30398487

Mechanisms of action of Ru(ii) polypyridyl complexes in living cells upon light irradiation.

Marta Jakubaszek1, Bruno Goud, Stefano Ferrari, Gilles Gasser.   

Abstract

The unique photophysical properties of Ru(ii) polypyridyl complexes make them very attractive candidates as photosensitisers in Photodynamic Therapy (PDT). However, to date, there are not many studies exploring in detail the mechanism(s) of action of such compounds in living systems upon light irradiation. This feature article provides an overview of the most in-depth biological studies on such compounds.

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Year:  2018        PMID： 30398487     DOI： 10.1039/c8cc05928d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  12 in total

Review 1.  Recent advances in noble metal complex based photodynamic therapy.

Authors:  Yanping Wu; Shumeng Li; Yuncong Chen; Weijiang He; Zijian Guo
Journal:  Chem Sci       Date:  2022-04-01       Impact factor: 9.969

2.  Classification of Metal-based Drugs According to Their Mechanisms of Action.

Authors:  Eszter Boros; Paul J Dyson; Gilles Gasser
Journal:  Chem       Date:  2019-11-07       Impact factor: 22.804

Review 3.  Metal-based photosensitizers for photodynamic therapy: the future of multimodal oncology?

Authors:  Sherri A McFarland; Arkady Mandel; Roger Dumoulin-White; Gilles Gasser
Journal:  Curr Opin Chem Biol       Date:  2019-11-20       Impact factor: 8.822

4.  cis-Locked Ru(II)-DMSO Precursors for the Microwave-Assisted Synthesis of Bis-Heteroleptic Polypyridyl Compounds.

Authors:  Alessio Vidal; Rudy Calligaro; Gilles Gasser; Roger Alberto; Gabriele Balducci; Enzo Alessio
Journal:  Inorg Chem       Date:  2021-04-28       Impact factor: 5.165

5.  Ruthenium-initiated polymerization of lactide: a route to remarkable cellular uptake for photodynamic therapy of cancer.

Authors:  Nancy Soliman; Luke K McKenzie; Johannes Karges; Emilie Bertrand; Mickaël Tharaud; Marta Jakubaszek; Vincent Guérineau; Bruno Goud; Marcel Hollenstein; Gilles Gasser; Christophe M Thomas
Journal:  Chem Sci       Date:  2020-01-30       Impact factor: 9.825

6.  Synthesis and Characterization of an Epidermal Growth Factor Receptor-Selective RuII Polypyridyl-Nanobody Conjugate as a Photosensitizer for Photodynamic Therapy.

Authors:  Johannes Karges; Marta Jakubaszek; Cristina Mari; Kristof Zarschler; Bruno Goud; Holger Stephan; Gilles Gasser
Journal:  Chembiochem       Date:  2019-10-22       Impact factor: 3.164

7.  A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy.

Authors:  Luke K McKenzie; Marie Flamme; Patrick S Felder; Johannes Karges; Frederic Bonhomme; Albert Gandioso; Christian Malosse; Gilles Gasser; Marcel Hollenstein
Journal:  RSC Chem Biol       Date:  2021-11-02

8.  Photocytotoxicity and photoinduced phosphine ligand exchange in a Ru(ii) polypyridyl complex.

Authors:  Sean J Steinke; Sayak Gupta; Eric J Piechota; Curtis E Moore; Jeremy J Kodanko; Claudia Turro
Journal:  Chem Sci       Date:  2022-02-01       Impact factor: 9.825

9.  Alkyne Functionalization of a Photoactivated Ruthenium Polypyridyl Complex for Click-Enabled Serum Albumin Interaction Studies.

Authors:  Anja Busemann; Can Araman; Ingrid Flaspohler; Alessandro Pratesi; Xue-Quan Zhou; Vincent H S van Rixel; Maxime A Siegler; Luigi Messori; Sander I van Kasteren; Sylvestre Bonnet
Journal:  Inorg Chem       Date:  2020-05-12       Impact factor: 5.165

Review 10.  Recent Emergence of Rhenium(I) Tricarbonyl Complexes as Photosensitisers for Cancer Therapy.

Authors:  Hui Shan Liew; Chun-Wai Mai; Mohd Zulkefeli; Thiagarajan Madheswaran; Lik Voon Kiew; Nicolas Delsuc; May Lee Low
Journal:  Molecules       Date:  2020-09-12       Impact factor: 4.411
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