| Literature DB >> 30397885 |
T A Bogush1, A A Basharina2,3, E A Bogush2, O M Ryabinina2, A S Tjulandina2, S A Tjulandin2.
Abstract
The quantitative immunofluorescence assay of serous ovarian cancer tissue for the expression of estrogen receptors (ERα and ERβ) revealed a higher expression level of ERβ in comparison with ERα in all surgical tumor samples investigated. Significant differences in the expression level of the markers were detected "from tumor to tumor." A high expression level of both ERα (≥ 25%) and ERβ (≥ 44%) in the tumor predicts a significantly longer progression-free survival time (p < 0.01) in the patients after the first line of platinum and taxane-based adjuvant chemotherapy.Entities:
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Year: 2018 PMID： 30397885 DOI： 10.1134/S1607672918050058
Source DB: PubMed Journal: Dokl Biochem Biophys ISSN： 1607-6729 Impact factor: 0.788