BACKGROUND: Jumping to conclusions (JTC), which is the proneness to require less information before forming beliefs or making a decision, has been related to formation and maintenance of delusions. Using data from the National Institute of Health Research Biomedical Research Centre Genetics and Psychosis (GAP) case-control study of first-episode psychosis (FEP), we set out to test whether the presence of JTC would predict poor clinical outcome at 4 years. METHODS: One-hundred and twenty-three FEP patients were assessed with the Positive and Negative Syndrome Scale (PANSS), Global Assessment of Functioning (GAF) and the probabilistic reasoning 'Beads' Task at the time of recruitment. The sample was split into two groups based on the presence of JTC bias. Follow-up data over an average of 4 years were obtained concerning clinical course and outcomes (remission, intervention of police, use of involuntary treatment - the Mental Health Act (MHA) - and inpatient days). RESULTS: FEP who presented JTC at baseline were more likely during the follow-up period to be detained under the MHA [adjusted OR 15.62, 95% confidence interval (CI) 2.92-83.54, p = 0.001], require intervention by the police (adjusted OR 14.95, 95% CI 2.68-83.34, p = 0.002) and have longer admissions (adjusted IRR = 5.03, 95% CI 1.91-13.24, p = 0.001). These associations were not accounted for by socio-demographic variables, IQ and symptom dimensions. CONCLUSIONS: JTC in FEP is associated with poorer outcome as indicated and defined by more compulsion police intervention and longer periods of admission. Our findings raise the question of whether the implementation of specific interventions to reduce JTC, such as Metacognition Training, may be a useful addition in early psychosis intervention programmes.
BACKGROUND: Jumping to conclusions (JTC), which is the proneness to require less information before forming beliefs or making a decision, has been related to formation and maintenance of delusions. Using data from the National Institute of Health Research Biomedical Research Centre Genetics and Psychosis (GAP) case-control study of first-episode psychosis (FEP), we set out to test whether the presence of JTC would predict poor clinical outcome at 4 years. METHODS: One-hundred and twenty-three FEP patients were assessed with the Positive and Negative Syndrome Scale (PANSS), Global Assessment of Functioning (GAF) and the probabilistic reasoning 'Beads' Task at the time of recruitment. The sample was split into two groups based on the presence of JTC bias. Follow-up data over an average of 4 years were obtained concerning clinical course and outcomes (remission, intervention of police, use of involuntary treatment - the Mental Health Act (MHA) - and inpatient days). RESULTS: FEP who presented JTC at baseline were more likely during the follow-up period to be detained under the MHA [adjusted OR 15.62, 95% confidence interval (CI) 2.92-83.54, p = 0.001], require intervention by the police (adjusted OR 14.95, 95% CI 2.68-83.34, p = 0.002) and have longer admissions (adjusted IRR = 5.03, 95% CI 1.91-13.24, p = 0.001). These associations were not accounted for by socio-demographic variables, IQ and symptom dimensions. CONCLUSIONS: JTC in FEP is associated with poorer outcome as indicated and defined by more compulsion police intervention and longer periods of admission. Our findings raise the question of whether the implementation of specific interventions to reduce JTC, such as Metacognition Training, may be a useful addition in early psychosis intervention programmes.
Authors: Giada Tripoli; Diego Quattrone; Laura Ferraro; Charlotte Gayer-Anderson; Victoria Rodriguez; Caterina La Cascia; Daniele La Barbera; Crocettarachele Sartorio; Fabio Seminerio; Ilaria Tarricone; Domenico Berardi; Andrei Szöke; Celso Arango; Andrea Tortelli; Pierre-Michel Llorca; Lieuwe de Haan; Eva Velthorst; Julio Bobes; Miguel Bernardo; Julio Sanjuán; Jose Luis Santos; Manuel Arrojo; Cristina Marta Del-Ben; Paulo Rossi Menezes; Jean-Paul Selten; Peter B Jones; Hannah E Jongsma; James B Kirkbride; Antonio Lasalvia; Sarah Tosato; Alex Richards; Michael O'Donovan; Bart Pf Rutten; Jim van Os; Craig Morgan; Pak C Sham; Robin M Murray; Graham K Murray; Marta Di Forti Journal: Psychol Med Date: 2020-04-24 Impact factor: 7.723
Authors: M Ferrer-Quintero; D Fernández; R López-Carrilero; I Birulés; A Barajas; E Lorente-Rovira; A Luengo; L Díaz-Cutraro; M Verdaguer; H García-Mieres; A Gutiérrez-Zotes; E Grasa; E Pousa; E Huerta-Ramos; T Pélaez; M L Barrigón; J Gómez-Benito; F González-Higueras; I Ruiz-Delgado; J Cid; S Moritz; J Sevilla-Llewellyn-Jones; S Ochoa Journal: Eur Arch Psychiatry Clin Neurosci Date: 2022-07-08 Impact factor: 5.760
Authors: Christian Rauschenberg; Ulrich Reininghaus; Margreet Ten Have; Ron de Graaf; Saskia van Dorsselaer; Claudia J P Simons; Nicole Gunther; Cécile Henquet; Lotta-Katrin Pries; Sinan Guloksuz; Maarten Bak; Jim van Os Journal: Psychol Med Date: 2020-03-16 Impact factor: 7.723
Authors: Ana Catalan; Stefania Tognin; Matthew J Kempton; Daniel Stahl; Gonzalo Salazar de Pablo; Barnaby Nelson; Christos Pantelis; Anita Riecher-Rössler; Rodrigo Bressan; Neus Barrantes-Vidal; Marie-Odile Krebs; Merete Nordentoft; Stephan Ruhrmann; Gabriele Sachs; Bart P F Rutten; Jim van Os; Lieuwe de Haan; Mark van der Gaag; Lucia R Valmaggia; Philip McGuire Journal: Psychol Med Date: 2020-10-06 Impact factor: 10.592