Literature DB >> 30390097

Epigenetic fates of gene silencing established by heterochromatin spreading in cell identity and genome stability.

R A Greenstein1,2, Bassem Al-Sady3.   

Abstract

Heterochromatin spreading, the propagation of repressive chromatin along the chromosome, is a reaction critical to genome stability and defense, as well as maintenance of unique cell fates. Here, we discuss the intrinsic properties of the spreading reaction and circumstances under which its products, formed distal to DNA-encoded nucleation sites, can be epigenetically maintained. Finally, we speculate that the epigenetic properties of heterochromatin evolved together with the need to stabilize cellular identity.

Entities:  

Keywords:  Cellular identity; Chromatin structure; DNA methylation; Epigenetic inheritance; Heterochromatin spreading; Histone 3 lysine 9 methylation; Histone turnover

Mesh：

Substances：

Year:  2018        PMID： 30390097      PMCID： PMC6452905          DOI： 10.1007/s00294-018-0901-1

Source DB:  PubMed          Journal:  Curr Genet        ISSN： 0172-8083            Impact factor:   3.886


  44 in total

1.  Requirement of heterochromatin for cohesion at centromeres.

Authors:  P Bernard; J F Maure; J F Partridge; S Genier; J P Javerzat; R C Allshire
Journal:  Science       Date:  2001-10-11       Impact factor: 47.728

2.  A recombinationally repressed region between mat2 and mat3 loci shares homology to centromeric repeats and regulates directionality of mating-type switching in fission yeast.

Authors:  S I Grewal; A J Klar
Journal:  Genetics       Date:  1997-08       Impact factor: 4.562

3.  Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication.

Authors:  Pierre-Olivier Estève; Hang Gyeong Chin; Andrea Smallwood; George R Feehery; Omkaram Gangisetty; Adam R Karpf; Michael F Carey; Sriharsa Pradhan
Journal:  Genes Dev       Date:  2006-11-03       Impact factor: 11.361

4.  Causal role for inheritance of H3K27me3 in maintaining the OFF state of a Drosophila HOX gene.

Authors:  Rory T Coleman; Gary Struhl
Journal:  Science       Date:  2017-03-16       Impact factor: 47.728

Review 5.  Replication-Coupled Nucleosome Assembly in the Passage of Epigenetic Information and Cell Identity.

Authors:  Albert Serra-Cardona; Zhiguo Zhang
Journal:  Trends Biochem Sci       Date:  2017-12-29       Impact factor: 13.807

6.  Recognition of hemi-methylated DNA by the SRA protein UHRF1 by a base-flipping mechanism.

Authors:  Kyohei Arita; Mariko Ariyoshi; Hidehito Tochio; Yusuke Nakamura; Masahiro Shirakawa
Journal:  Nature       Date:  2008-09-03       Impact factor: 49.962

Review 7.  Constitutive heterochromatin formation and transcription in mammals.

Authors:  Nehmé Saksouk; Elisabeth Simboeck; Jérôme Déjardin
Journal:  Epigenetics Chromatin       Date:  2015-01-15       Impact factor: 4.954

8.  DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation.

Authors:  Xiaoyi Wang; Danesh Moazed
Journal:  Science       Date:  2017-03-16       Impact factor: 47.728

9.  HDAC-mediated suppression of histone turnover promotes epigenetic stability of heterochromatin.

Authors:  Ozan Aygün; Sameet Mehta; Shiv I S Grewal
Journal:  Nat Struct Mol Biol       Date:  2013-04-21       Impact factor: 15.369

10.  Accurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA Replication.

Authors:  Nazaret Reverón-Gómez; Cristina González-Aguilera; Kathleen R Stewart-Morgan; Nataliya Petryk; Valentin Flury; Simona Graziano; Jens Vilstrup Johansen; Janus Schou Jakobsen; Constance Alabert; Anja Groth
Journal:  Mol Cell       Date:  2018-08-23       Impact factor: 17.970
View more
  3 in total

1.  Monitoring of switches in heterochromatin-induced silencing shows incomplete establishment and developmental instabilities.

Authors:  Farah Bughio; Gary R Huckell; Keith A Maggert
Journal:  Proc Natl Acad Sci U S A       Date:  2019-09-16       Impact factor: 11.205

Review 2.  Genome protection: histone H4 and beyond.

Authors:  Kundan Kumar; Romila Moirangthem; Rupinder Kaur
Journal:  Curr Genet       Date:  2020-06-17       Impact factor: 3.886

3.  Transgenerational effect of drug-mediated inhibition of LSD1 on eye pigment expression in Drosophila.

Authors:  Sigrid Hoyer-Fender
Journal:  BMC Ecol       Date:  2020-11-23       Impact factor: 2.964
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.