Literature DB >> 30387787

Asymmetric alkylations and aldol reactions: (1S,2R)-2-aminocyclopentan-1-ol derived new chiral auxiliary.

Arun K Ghosh1, Hanna Cho1, Masanobu Onishi1.   

Abstract

Asymmetric alkylation and aldol reaction of optically active (1S,2R)-2-aminocyclopentan-l-ol derived chiral auxiliary proceeded with excellent diastereofacial selectivities (>99%) and isolated yields.

Entities:  

Year:  1997        PMID： 30387787      PMCID： PMC6207082          DOI： 10.1016/S0957-4166(97)00065-7

Source DB:  PubMed          Journal:  Tetrahedron Asymmetry        ISSN： 0957-4166


  7 in total

1.  1,2-Amino Alcohols and Their Heterocyclic Derivatives as Chiral Auxiliaries in Asymmetric Synthesis.

Authors:  David J. Ager; Indra Prakash; David R. Schaad
Journal:  Chem Rev       Date:  1996-03-28       Impact factor: 60.622

2.  Toward the Development of a General Chiral Auxiliary. 5. High Diastereofacial Selectivity in Cycloadditions with Trienol Silyl Ethers: An Application to an Enantioselective Synthesis of (-)-Cassioside.

Authors:  Robert K Boeckman; Yugang Liu
Journal:  J Org Chem       Date:  1996-11-15       Impact factor: 4.354

3.  Total Synthesis of (+)-Sinefungin.

Authors:  Arun K. Ghosh; Wenming Liu
Journal:  J Org Chem       Date:  1996-09-06       Impact factor: 4.354

4.  Highly Enantioselective Aldol Reaction: Development of a New Chiral Auxiliary from cis-1-Amino-2-hydroxyindan.

Authors:  Arun K Ghosh; Tien T Duong; Sean P McKee
Journal:  J Chem Soc Chem Commun       Date:  1992

5.  A Convergent, Enantioselective Total Synthesis of Hapalosin: A Drug with Multidrug-Resistance Reversing Activity.

Authors:  Arun K Ghosh; Wenming Liu; Yibo Xu; Zhidong Chen
Journal:  Angew Chem Int Ed Engl       Date:  1996-01-19       Impact factor: 15.336

6.  Diphenylphosphoryl azide. A new convenient reagent for a modified Curtus reaction and for the peptide synthesis.

Authors:  T Shioiri; K Ninomiya; S Yamada
Journal:  J Am Chem Soc       Date:  1972-08-23       Impact factor: 15.419

7.  Potent HIV-1 Protease Inhibitors: Stereoselective Synthesis of a Dipeptide Mimic.

Authors:  Arun K Ghosh; Sean P McKee; Wayne J Thompson; Paul L Darke; Joan C Zugay
Journal:  J Org Chem       Date:  1993-02       Impact factor: 4.354
  7 in total
  1 in total

1.  Stereodivergent Nucleophilic Additions to Racemic β-Oxo Acid Derivatives: Fast Addition Outcompetes Stereoconvergence in the Archetypal Configurationally Unstable Electrophile.

Authors:  Pedro De Jesús Cruz; Evan T Crawford; Shubin Liu; Jeffrey S Johnson
Journal:  J Am Chem Soc       Date:  2021-09-27       Impact factor: 16.383
  1 in total

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