Literature DB >> 30385886

Disparities in genetic services utilization in a random sample of young breast cancer survivors.

Christos Nikolaidis1, Debra Duquette2,3, Kari E Mendelsohn-Victor4, Beth Anderson3, Glenn Copeland3, Kara J Milliron5, Sofia D Merajver6,7, Nancy K Janz6, Laurel L Northouse4, Sonia A Duffy8, Maria C Katapodi9,10.   

Abstract

PURPOSE: Increasing use of genetic services (counseling/testing) among young breast cancer survivors (YBCS) can help decrease breast cancer incidence and mortality. The study examined use of genetic services between Black and White/Other YBCS, attitudes and knowledge of breast cancer risk factors, and reasons for disparities in using genetic services.
METHODS: We used baseline data from a randomized control trial including a population-based, stratified random sample of 3000 potentially eligible YBCS, with oversampling of Black YBCS.
RESULTS: Among 883 YBCS (353 Black, 530 White/Other) were significant disparities between the two racial groups. More White/Other YBCS had received genetic counseling and had genetic testing than Blacks. Although White/Other YBCS resided farther away from board-certified genetic counseling centers, they had fewer barriers to access these services. Black race, high out-of-pocket costs, older age, and more years since diagnosis were negatively associated with use of genetic services. Black YBCS had lower knowledge of breast cancer risk factors. Higher education and genetic counseling were associated with higher genetic knowledge.
CONCLUSION: Racial inequalities of cost-related access to care and education create disparities in genetic services utilization. System-based interventions that reduce socioeconomic disparities and empower YBCS with genetic knowledge, as well as physician referrals, can increase access to genetic services.

Entities:  

Keywords:  cancer registry; distance as a barrier to access genetic services; equity in using cancer genetic services; geocoding; young breast cancer survivors

Mesh:

Year:  2018        PMID: 30385886     DOI: 10.1038/s41436-018-0349-1

Source DB:  PubMed          Journal:  Genet Med        ISSN: 1098-3600            Impact factor:   8.822


  6 in total

1.  Interest in genetic testing and risk-reducing behavioral changes: results from a community health assessment in New York City.

Authors:  Sarah M Lima; Meaghan Nazareth; Karen M Schmitt; Andria Reyes; Elaine Fleck; Gary K Schwartz; Mary Beth Terry; Grace C Hillyer
Journal:  J Community Genet       Date:  2022-10-13

2.  Associations of sociodemographic and clinical factors with gastrointestinal cancer risk assessment appointment completion.

Authors:  Jessica E Ebrahimzadeh; Jessica M Long; Louise Wang; John T Nathanson; Shazia Mehmood Siddique; Anil K Rustgi; David S Goldberg; Bryson W Katona
Journal:  J Genet Couns       Date:  2020-03-30       Impact factor: 2.537

Review 3.  An Overview of PARP Inhibitors for the Treatment of Breast Cancer.

Authors:  Laura Cortesi; Hope S Rugo; Christian Jackisch
Journal:  Target Oncol       Date:  2021-03-12       Impact factor: 4.493

4.  Genetic Literacy and Communication of Genetic Information in Families Concerned with Hereditary Breast and Ovarian Cancer: A Cross-Study Comparison in Two Countries and within a Timeframe of More Than 10 Years.

Authors:  Carla Pedrazzani; Chang Ming; Nicole Bürki; Maria Caiata-Zufferey; Pierre O Chappuis; Debra Duquette; Karl Heinimann; Viola Heinzelmann-Schwarz; Rossella Graffeo-Galbiati; Sofia D Merajver; Kara J Milliron; Christian Monnerat; Olivia Pagani; Manuela Rabaglio; Maria C Katapodi
Journal:  Cancers (Basel)       Date:  2021-12-13       Impact factor: 6.639

5.  Increasing access to individualized medicine: a matched-cohort study examining Latino participant experiences of genomic screening.

Authors:  Joel E Pacyna; Gabriel Q Shaibi; Alex Lee; Jamie O Byrne; Idali Cuellar; Erica J Sutton; Valentina Hernandez; Noralane M Lindor; Davinder Singh; Iftikhar J Kullo; Richard R Sharp
Journal:  Genet Med       Date:  2021-01-26       Impact factor: 8.822

6.  Uptake of genetic counseling and testing in a clinic-based population of women with breast cancer.

Authors:  Alexandra Wehbe; Mark Manning; Hadeel Assad; Kristen S Purrington; Michael S Simon
Journal:  Cancer Med       Date:  2022-03-23       Impact factor: 4.711

  6 in total

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