Literature DB >> 3038000

In vitro activity of zinc salts against human rhinoviruses.

F C Geist, J A Bateman, F G Hayden.   

Abstract

The antiviral activity of zinc salts against rhinovirus types 1A and 39 was assayed by yield reduction and inhibition of cytopathic effect in cell culture. The findings indicate that the zinc salts tested have low in vitro therapeutic indices and suggest that the possible beneficial effects of zinc lozenges in reducing cold symptoms may not be related to selective antirhinovirus activity.

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Year:  1987        PMID： 3038000      PMCID： PMC174791          DOI： 10.1128/AAC.31.4.622

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Effect of zinc ions on the synthesis of herpes simplex virus DNA in infected BSC-1 cells.

Authors:  J Shlomai; Y Asher; Y J Gordon; U Olshevsky; Y Becker
Journal:  Virology       Date:  1975-07       Impact factor: 3.616

2.  Inhibition by zinc of rhinovirus protein cleavage: interaction of zinc with capsid polypeptides.

Authors:  B D Korant; B E Butterworth
Journal:  J Virol       Date:  1976-04       Impact factor: 5.103

3.  Zinc ions inhibit replication of rhinoviruses.

Authors:  B D Korant; J C Kauer; B E Butterworth
Journal:  Nature       Date:  1974-04-12       Impact factor: 49.962

4.  Zinc and infection.

Authors:  B Sugarman
Journal:  Rev Infect Dis       Date:  1983 Jan-Feb

5.  Reduction in duration of common colds by zinc gluconate lozenges in a double-blind study.

Authors:  G A Eby; D R Davis; W W Halcomb
Journal:  Antimicrob Agents Chemother       Date:  1984-01       Impact factor: 5.191

6.  Inhibition of vaccinia virus maturation by zinc chloride.

Authors:  E Katz; E Margalith
Journal:  Antimicrob Agents Chemother       Date:  1981-02       Impact factor: 5.191

7.  Inhibition of Chlamydia trachomatis growth in McCoy, HeLa, and human prostate cells by zinc.

Authors:  S B Greenberg; D Harris; P Giles; R R Martin; R J Wallace
Journal:  Antimicrob Agents Chemother       Date:  1985-06       Impact factor: 5.191
  7 in total
  20 in total

1.  How to treat influenza and colds.

Authors:  M C Kim; N P Lee
Journal:  West J Med       Date:  2000-04

2.  Zinc acetate/carrageenan gels exhibit potent activity in vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge.

Authors:  José A Fernández-Romero; Ciby J Abraham; Aixa Rodriguez; Larisa Kizima; Ninochka Jean-Pierre; Radhika Menon; Othell Begay; Samantha Seidor; Brian E Ford; Pedro I Gil; Jennifer Peters; David Katz; Melissa Robbiani; Thomas M Zydowsky
Journal:  Antimicrob Agents Chemother       Date:  2011-11-07       Impact factor: 5.191

3.  Differential effects of zinc in severe pneumonia in children.

Authors:  Rashmi Ranjan Das
Journal:  Indian J Pediatr       Date:  2011-05-12       Impact factor: 1.967

4.  Two randomized controlled trials of zinc gluconate lozenge therapy of experimentally induced rhinovirus colds.

Authors:  B M Farr; E M Conner; R F Betts; J Oleske; A Minnefor; J M Gwaltney
Journal:  Antimicrob Agents Chemother       Date:  1987-08       Impact factor: 5.191

5.  Efficacy and toxicity of zinc salts as candidate topical microbicides against vaginal herpes simplex virus type 2 infection.

Authors:  Nigel Bourne; Rachael Stegall; Raquel Montano; Michael Meador; Lawrence R Stanberry; Gregg N Milligan
Journal:  Antimicrob Agents Chemother       Date:  2005-03       Impact factor: 5.191

Review 6.  Non-specific microbicide product development: then and now.

Authors:  Joseph W Romano; Melissa Robbiani; Gustavo F Doncel; Thomas Moench
Journal:  Curr HIV Res       Date:  2012-01-01       Impact factor: 1.581

7.  Inhibition of polyprotein processing and RNA replication of human rhinovirus by pyrrolidine dithiocarbamate involves metal ions.

Authors:  B M Krenn; B Holzer; E Gaudernak; A Triendl; F J van Kuppeveld; J Seipelt
Journal:  J Virol       Date:  2005-11       Impact factor: 5.103

8.  Stability constants of zinc complexes affect common cold treatment results.

Authors:  G A Eby
Journal:  Antimicrob Agents Chemother       Date:  1988-04       Impact factor: 5.191

9.  Zinc for the common cold.

Authors:  J C Godfrey
Journal:  Antimicrob Agents Chemother       Date:  1988-04       Impact factor: 5.191

10.  The changes of metabolism balance of zinc and copper in gastric juice with widely varying dietary zinc intake.

Authors:  P L Leung; X L Li
Journal:  Biol Trace Elem Res       Date:  1993-10       Impact factor: 3.738
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