Literature DB >> 3037864

Histamine dependent cAMP generating system in rabbit CNS: interaction with various neuroregulators.

B Sek, A Sebastjanska, J Z Nowak.   

Abstract

Histamine (HI) potently stimulated, through H2-receptors, cAMP accumulation in slices of the rabbit cerebral cortex (EC50: 15 microM; maximum stimulation: 300-450% of the basal level). Combination of L-noradrenaline or L-adrenaline and adenosine with HI showed synergistic and additive effects, respectively. Carbachol, arecoline and pilocarpine had no effect, while oxotremorine and tremorine increased and decreased the HI response when used at low or high concentrations, respectively.

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Year:  1987        PMID： 3037864     DOI： 10.1007/BF02074681

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  8 in total

1.  The role of calcium in the regulation of cyclic nucleotide levels in brain slices of rat and guinea pig.

Authors:  U Schwabe; Y Ohga; J W Daly
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1978-04       Impact factor: 3.000

2.  Pharmacological characterization of histamine receptors mediating the stimulation of cyclic AMP accumulation in slices from guinea-pig hippocampus.

Authors:  J M Palacios; M Garbarg; G Barbin; J C Schwartz
Journal:  Mol Pharmacol       Date:  1978-11       Impact factor: 4.436

3.  Pharmacological properties of histamine-sensitive adenylate cyclase from mammalian brain.

Authors:  P D Kanof; P Greengard
Journal:  J Pharmacol Exp Ther       Date:  1979-04       Impact factor: 4.030

4.  A simple and sensitive saturation assay method for the measurement of adenosine 3':5'-cyclic monophosphate.

Authors:  B L Brown; J D Albano; R P Ekins; A M Sgherzi
Journal:  Biochem J       Date:  1971-02       Impact factor: 3.857

5.  Studies on adenosine 3',5'-phosphate in rabbit cerebral cortex.

Authors:  S Kakiuchi; T W Rall
Journal:  Mol Pharmacol       Date:  1968-07       Impact factor: 4.436

6.  Histamine H1-agonist potentiation of adenosine-stimulated cyclic AMP accumulation in slices of guinea-pig cerebral cortex: comparison of response and binding parameters.

Authors:  P R Daum; S J Hill; J M Young
Journal:  Br J Pharmacol       Date:  1982-10       Impact factor: 8.739

7.  Characterization of histamine receptors mediating the stimulation of cyclic AMP accumulation in rabbit cerebral cortical slices.

Authors:  M Al-Gadi; S J Hill
Journal:  Br J Pharmacol       Date:  1985-08       Impact factor: 8.739

8.  Accumulation of inositol phosphates and cyclic AMP in guinea-pig cerebral cortical preparations. Effects of norepinephrine, histamine, carbamylcholine and 2-chloroadenosine.

Authors:  E B Hollingsworth; J W Daly
Journal:  Biochim Biophys Acta       Date:  1985-11-20
  8 in total
  2 in total

1.  Histamine-mediated regulation of cAMP levels and inositol phosphate metabolism in isolated rabbit retina.

Authors:  J Z Nowak; B Sek; B Szkiel
Journal:  Agents Actions       Date:  1989-04

2.  Histamine dependent cyclic AMP generating system in rabbit CNS: interaction with neuroregulators and forskolin.

Authors:  B Sek; A Sebastjanska; J Z Nowak
Journal:  Agents Actions       Date:  1988-04
  2 in total

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