| Literature DB >> 2899381 |
B Sek1, A Sebastjanska, J Z Nowak.
Abstract
Histamine (HI) potently stimulated, through H2-receptors, cAMP accumulation in rabbit cerebral cortical slices but not in retinal pieces. The action of HI in the cerebral cortex was not significantly affected by dopamine, serotonin, melatonin and GABA-ergic drugs. Forskolin markedly stimulated cAMP accumulation both in the cerebral cortex and retina. There was a synergistic interaction between HI and forskolin in the cerebral cortex, whereas in the retina HI decreased the forskolin-activated cAMP accumulation.Entities:
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Year: 1988 PMID: 2899381 DOI: 10.1007/bf02142551
Source DB: PubMed Journal: Agents Actions ISSN: 0065-4299