Literature DB >> 30377755

A randomized clinical trial comparing the initial vascular approach to the inferior mesenteric vein versus the inferior mesenteric artery in laparoscopic surgery of rectal cancer and sigmoid colon cancer.

Pere Planellas1, Helena Salvador2, Ramon Farrés2, Núria Gómez2, David Julià2, Júlia Gil2, Marcel Pujadas2, Franco Marinello2, Lídia Cornejo3, Antoni Codina2.   

Abstract

BACKGROUND: The inferior mesenteric artery approach with a selective lateral splenic flexure mobilization is the most widely used initial step in laparoscopic rectal and left colon surgery. Surgery started through the inferior mesenteric vein (IMV) with systematic medial mobilization (MM) has some theoretical advantages that have never been analyzed in a clinical trial. The aim of this study was to compare the two techniques with regards to surgical technique variables (conversion, surgical time, bleeding, morbidity, and mortality) and pathological outcomes.
METHODS: A single-blinded, randomized, controlled trial of patients operated electively by laparoscopic with curative intention for rectal or sigmoid cancer was performed at a single, specialized colorectal surgery department from April 2016 to October 2017.
RESULTS: 49 patients were included in each group. There were no statistical differences in patient demographics between the two approaches. Pathological outcomes did not differ between the two groups. Intra-operative characteristics showed a higher conversion rate in patients in which the inferior mesenteric artery was dissected first (p = 0.031). The artery approach also increased intra-operative bleeding (p = 0.049), but there were no differences regarding operative time. On multivariate analysis, the artery approach was associated with a higher risk of conversion (OR 8.68; p = 0.050). Post-operatory complications did not differ between artery and vein dissection.
CONCLUSIONS: In our study, the initial approach by the IMV with a systematic MM of the splenic flexure has allowed us to reduce the conversion rate without increasing complications or the surgical time. No differences were observed in the pathological results. Both approaches seem to be safe and effective and well-trained laparoscopic surgeons should have the two techniques available to them for use as needed.

Entities:  

Keywords:  Colorectal cancer; Inferior mesenteric vein; Rectal cancer; Splenic colon flexure; Vascular approach

Mesh:

Year:  2018        PMID: 30377755     DOI: 10.1007/s00464-018-6551-z

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  14 in total

Review 1.  Laparoscopic versus open resection for colorectal cancer: a metaanalysis of oncologic outcomes.

Authors:  Timothy D Jackson; Gilaad G Kaplan; Goffredo Arena; John H Page; Selwyn O Rogers
Journal:  J Am Coll Surg       Date:  2007-03       Impact factor: 6.113

2.  Laparoscopic medial-to-lateral colon dissection: how and why.

Authors:  Alessio Pigazzi; Minia Hellan; Douglas R Ewing; Benjamin I Paz; Garth H Ballantyne
Journal:  J Gastrointest Surg       Date:  2007-06       Impact factor: 3.452

3.  Lengthening of the colon for low rectal anastomosis in a cadaveric study: how much can we gain?

Authors:  S Thum-umnuaysuk; A Boonyapibal; Y Y Geng; J Pattana-Arun
Journal:  Tech Coloproctol       Date:  2012-11-15       Impact factor: 3.781

Review 4.  High ligation of the inferior mesenteric artery in rectal cancer surgery.

Authors:  Jin-Ichi Hida; Kiyotaka Okuno
Journal:  Surg Today       Date:  2012-10-07       Impact factor: 2.549

5.  Factors affecting difficulty of laparoscopic surgery for left-sided colon cancer.

Authors:  Takashi Akiyoshi; Hiroya Kuroyanagi; Masatoshi Oya; Masashi Ueno; Yoshiya Fujimoto; Tsuyoshi Konishi; Toshiharu Yamaguchi
Journal:  Surg Endosc       Date:  2010-04-10       Impact factor: 4.584

6.  Inferior pancreatic approach for laparoscopic splenic flexure mobilization.

Authors:  T Kumamoto; H Shinohara; K Tomizawa; Y Hanaoka; S Toda; N Takemura; J Moriyama; S Matoba; H Kuroyanagi
Journal:  Tech Coloproctol       Date:  2017-12-18       Impact factor: 3.781

Review 7.  A meta-analysis to determine the oncological implications of conversion in laparoscopic colorectal cancer surgery.

Authors:  C Clancy; D P O'Leary; J P Burke; H P Redmond; J C Coffey; M J Kerin; E Myers
Journal:  Colorectal Dis       Date:  2015-06       Impact factor: 3.788

8.  Enhanced survival of patients with colon and rectal cancer is based upon wide anatomic resection.

Authors:  W E Enker; U T Laffer; G E Block
Journal:  Ann Surg       Date:  1979-09       Impact factor: 12.969

9.  Laparoscopic colectomy for colon cancer: comparable to conventional oncologic surgery?

Authors:  Ricardo M Bonnor; Kirk A Ludwig
Journal:  Clin Colon Rectal Surg       Date:  2005-08

10.  Level of arterial ligation in sigmoid colon and rectal cancer surgery.

Authors:  Koji Yasuda; Kazushige Kawai; Soichiro Ishihara; Koji Murono; Kensuke Otani; Takeshi Nishikawa; Toshiaki Tanaka; Tomomichi Kiyomatsu; Keisuke Hata; Hiroaki Nozawa; Hironori Yamaguchi; Shigeo Aoki; Hideyuki Mishima; Tsunehiko Maruyama; Akihiro Sako; Toshiaki Watanabe
Journal:  World J Surg Oncol       Date:  2016-04-01       Impact factor: 2.754

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