Literature DB >> 30374418

Instillation Negative Pressure Wound Therapy: An Effective Tool for Complex Spine Wounds.

Julie M West1, Sumanas W Jordan1, Ehud Mendel2,3, Safdar N Khan3, Rajiv Y Chandawarkar1,3, Ian L Valerio1,3.   

Abstract

Objective: Infection prevention in spinal surgeries involving implantation of hardware is of utmost priority. Furthermore, successful eradication of infection in hardware salvage is likewise critical in maintaining the long-term retention of the spinal hardware construct. Approach: We report a retrospective case series of three cases where the utilization of a VAC with instillation (VACi) in conjunction with surgical debridement aided in infection control and eradication for both preimplantation and hardware salvage spine patients.
Results: Three patients were included. In case 1, VACi was utilized in conjunction with surgical debridement and IV antibiotics in the setting of acute preoperative infection to eradicate infection and enable necessary spinal hardware implementation. Cases 2 and 3 are representative of VACi for salvage of exposed spinal hardware in both the early and delayed infection presentation settings. In both cases, patients developed postoperative infections following spinal instrumentation VACi was utilized in conjunction with surgical debridement and IV antibiotics. Hardware removal was avoided in both cases. All three patients healed completely without residual evidence of infection. Innovation: VACi showed its effectiveness in timely infection eradication before spinal hardware instrumentation and with postoperative spine hardware salvage.
Conclusion: This case series demonstrates that VACi can provide infection eradication both preoperatively in high-risk surgical sites, facilitating necessary hardware implementation and postoperatively in situations of hardware salvage.

Entities:  

Keywords:  VAC with instillation; debridement; infection; negative pressure

Year:  2018        PMID: 30374418      PMCID: PMC6203227          DOI: 10.1089/wound.2018.0793

Source DB:  PubMed          Journal:  Adv Wound Care (New Rochelle)        ISSN: 2162-1918            Impact factor:   4.730


  8 in total

Review 1.  Negative pressure wound therapy: past, present and future.

Authors:  Dennis P Orgill; Lauren R Bayer
Journal:  Int Wound J       Date:  2013-12       Impact factor: 3.315

Review 2.  Uses of negative pressure wound therapy in orthopedic trauma.

Authors:  Mark J Gage; Richard S Yoon; Kenneth A Egol; Frank A Liporace
Journal:  Orthop Clin North Am       Date:  2014-12-17       Impact factor: 2.472

3.  The impact of negative-pressure wound therapy with instillation compared with standard negative-pressure wound therapy: a retrospective, historical, cohort, controlled study.

Authors:  Paul J Kim; Christopher E Attinger; John S Steinberg; Karen K Evans; Kelly A Powers; Rex W Hung; Jesse R Smith; Zinnia M Rocha; Larry Lavery
Journal:  Plast Reconstr Surg       Date:  2014-03       Impact factor: 4.730

Review 4.  Evidence-based management of deep wound infection after spinal instrumentation.

Authors:  Rishi R Lall; Albert P Wong; Rohan R Lall; Cort D Lawton; Zachary A Smith; Nader S Dahdaleh
Journal:  J Clin Neurosci       Date:  2014-10-11       Impact factor: 1.961

Review 5.  Periprosthetic joint infection.

Authors:  Bhaveen H Kapadia; Richard A Berg; Jacqueline A Daley; Jan Fritz; Anil Bhave; Michael A Mont
Journal:  Lancet       Date:  2015-06-28       Impact factor: 79.321

6.  First experiences with negative pressure wound therapy and instillation in the treatment of infected orthopaedic implants: a clinical observational study.

Authors:  Burkhard Lehner; Wim Fleischmann; Rolf Becker; Gerrolt N Jukema
Journal:  Int Orthop       Date:  2011-05-17       Impact factor: 3.075

7.  VAC therapy for wound management in patients with contraindications to surgical treatment.

Authors:  Luca Negosanti; Rossella Sgarzani; Parissa Nejad; Valentina Pinto; Beatrice Tavaniello; Stefano Palo; Carlo Maria Oranges; Erich Fabbri; Veronica Vietti Michelina; Guido Zannetti; Paolo Giovanni Morselli; Riccardo Cipriani
Journal:  Dermatol Ther       Date:  2012 May-Jun       Impact factor: 2.851

Review 8.  Biofilms in periprosthetic orthopedic infections.

Authors:  Stephen J McConoughey; Rob Howlin; Jeff F Granger; Maurice M Manring; Jason H Calhoun; Mark Shirtliff; Sandeep Kathju; Paul Stoodley
Journal:  Future Microbiol       Date:  2014       Impact factor: 3.165

  8 in total
  7 in total

1.  Instillation negative pressure wound therapy: An effective approach for hardware salvage.

Authors:  Jason D Hehr; Trevor S Hodson; Julie M West; Steven A Schulz; Stephen J Poteet; Rajiv Y Chandawarkar; Ian L Valerio
Journal:  Int Wound J       Date:  2019-12-19       Impact factor: 3.315

2.  Instillation Negative Pressure Wound Therapy: A Role for Infected LVAD Salvage.

Authors:  Trevor Hodson; Julie M West; Stephen J Poteet; Peter H Lee; Ian L Valerio
Journal:  Adv Wound Care (New Rochelle)       Date:  2019-03-05       Impact factor: 4.730

3.  Modified negative pressure wound therapy as an adjunct to antibiotics in the treatment of orthopaedic infected metalwork.

Authors:  Selina Summers; Natasha Faye Daniels; Azeem Thahir; Matija Krkovic
Journal:  Eur J Orthop Surg Traumatol       Date:  2021-10-02

4.  Economic model to estimate cost of negative pressure wound therapy with instillation vs control therapies for hospitalised patients in the United States, Germany, and United Kingdom.

Authors:  Paul J Kim; Siobhan Lookess; Christine Bongards; Leah Passmore Griffin; Allen Gabriel
Journal:  Int Wound J       Date:  2021-09-28       Impact factor: 3.099

5.  Salvaging the Unsalvageable: Negative Pressure Wound Therapy for Severe Infection of Prosthetic Breast Reconstruction.

Authors:  Farid Meybodi; Negin Sedaghat; Elisabeth Elder; James French; Kristian Adams; Jeremy Hsu; Kavitha Kanesalingam; Meagan Brennan
Journal:  Plast Reconstr Surg Glob Open       Date:  2021-03-26

6.  Negative pressure wound therapy with instillation: International consensus guidelines update.

Authors:  Paul J Kim; Christopher E Attinger; Thomas Constantine; Brett D Crist; Elizabeth Faust; Christoph R Hirche; Lawrence A Lavery; Valerie J Messina; Norihiko Ohura; Laurie J Punch; Garrett A Wirth; Ibby Younis; Luc Téot
Journal:  Int Wound J       Date:  2019-10-30       Impact factor: 3.315

7.  Clinical application and efficacy of negative pressure wound therapy with instillation and dwell time (NPWTi-d): A systematic review and meta-analysis.

Authors:  Muholan Kanapathy; Angelos Mantelakis; Natasha Khan; Ibby Younis; Afshin Mosahebi
Journal:  Int Wound J       Date:  2020-10-05       Impact factor: 3.315

  7 in total

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