Literature DB >> 30364742

Rates of Mortality in Lumbar Spine Surgery and Factors Associated With Its Occurrence Over a 10-Year Period: A Study of 803,949 Patients in the Nationwide Inpatient Sample.

Gregory Wyatt Poorman1, John Y Moon1, Charles Wang1, Samantha R Horn1, Bryan M Beaubrun1, Olivia J Bono1, Anne-Marie Francis1, Cyrus M Jalai1, Peter G Passias1.   

Abstract

BACKGROUND: The rate of mortality in surgical procedures involving the lumbar spine has historically been low, and as a result, there has been difficulty providing accurate quantitative mortality rates to patients in the preoperative planning phase. Awareness of these mortality rates is essential in reducing postoperative complications and improving outcomes. Additionally, mortality rates can be influenced by procedure type and patient profile, including demographics and comorbidities. The purpose of this study is to assess rates and risk factors associated with mortality in surgical procedures involving the lumbar spine using a large national database.
METHODS: The Nationwide Inpatient Sample database was reviewed from 2003 to 2012. A total of 803,949 patients age 18 years or older were identified by ICD-9CM procedure codes for spinal fusion or decompression of the lumbar spine. Mortality was stratified based on type of procedure (simple or complex fusion, decompression), patient demographics and comorbidities, and in-hospital complications. Binary logistic regression was used to identify the risk of death while controlling for comorbidities, race, sex, and procedure performed. Significance was defined as P < .05 differences relative to the overall cohort.
RESULTS: Mortality for all patients requiring surgery of the lumbar spine was 0.13%. Mortality based on procedure type was 0.105% for simple fusions, 0.321% for complex fusions, and 0.081% for decompression only. Increased mortality was observed demographically in patients who were male (odds ratio [OR]: 1.75; 95% confidence interval [CI]: 1.51-2.03), black (OR: 1.40; CI: 1.10-1.79), ages 65-74 (OR: 1.46; CI: 1.25-1.70), and age 75+ (OR: 2.70; CI: 2.30-3.17). Comorbidities associated with the greatest increase in mortality were mild (OR: 10.04; CI: 7.76-13.01) and severe (OR: 26.47; CI: 16.03-43.70) liver disease and congestive heart failure (OR: 4.57; CI: 3.77-5.53). The complications with the highest mortality rates were shock (OR: 20.67; CI: 13.89-30.56) and pulmonary embolism (OR: 20.15; CI: 14.01-29.00).
CONCLUSIONS: From 2003 to 2012, the overall mortality rate in 803,949 lumbar spine surgery patients was 0.13%. Risk factors that were significantly associated with increased mortality rates were male gender, black race, and ages 65-74 and 75+. Comorbidities associated with an increased mortality rate were mild and severe liver disease and congestive heart failure. Inpatient complications with the highest mortality rates were shock and pulmonary embolism. These findings can be helpful to surgeons providing preoperative counseling for patients considering elective lumbar procedures and for allocating resources to treat and prevent perioperative complications leading to mortality. LEVEL OF EVIDENCE: 3.

Entities:  

Keywords:  NIS database; lumbar spine surgery; mortality incidence

Year:  2018        PMID: 30364742      PMCID: PMC6198620          DOI: 10.14444/5076

Source DB:  PubMed          Journal:  Int J Spine Surg        ISSN: 2211-4599


  20 in total

1.  Perioperative morbidity and mortality after anterior, posterior, and anterior/posterior spine fusion surgery.

Authors:  Stavros G Memtsoudis; Vassilios I Vougioukas; Yan Ma; Licia K Gaber-Baylis; Federico P Girardi
Journal:  Spine (Phila Pa 1976)       Date:  2011-10-15       Impact factor: 3.468

2.  Complications and Mortality After Lumbar Spinal Fusion in Elderly Patients With Late Stage Renal Disease.

Authors:  Varun Puvanesarajah; Amit Jain; Daniel E Hess; Adam L Shimer; Francis H Shen; Hamid Hassanzadeh
Journal:  Spine (Phila Pa 1976)       Date:  2016-11-01       Impact factor: 3.468

3.  Time elapsed after ischemic stroke and risk of adverse cardiovascular events and mortality following elective noncardiac surgery.

Authors:  Mads E Jørgensen; Christian Torp-Pedersen; Gunnar H Gislason; Per Føge Jensen; Siv Mari Berger; Christine Benn Christiansen; Charlotte Overgaard; Michelle D Schmiegelow; Charlotte Andersson
Journal:  JAMA       Date:  2014-07-16       Impact factor: 56.272

4.  Complications and mortality in cervical spine surgery: racial differences.

Authors:  Richard L Skolasky; Roland J Thorpe; Stephen T Wegener; Lee H Riley
Journal:  Spine (Phila Pa 1976)       Date:  2014-08-15       Impact factor: 3.468

5.  Congestive Heart Failure and Noncardiac Operations: Risk of Serious Morbidity, Readmission, Reoperation, and Mortality.

Authors:  Florence E Turrentine; Min-Woong Sohn; Rayford Scott Jones
Journal:  J Am Coll Surg       Date:  2016-03-31       Impact factor: 6.113

6.  Cerebral vascular accidents after lumbar spine fusion.

Authors:  Alejandro Marquez-Lara; Sreeharsha V Nandyala; Steven J Fineberg; Kern Singh
Journal:  Spine (Phila Pa 1976)       Date:  2014-04-15       Impact factor: 3.468

7.  Rates and causes of mortality associated with spine surgery based on 108,419 procedures: a review of the Scoliosis Research Society Morbidity and Mortality Database.

Authors:  Justin S Smith; Dwight Saulle; Ching-Jen Chen; Lawrence G Lenke; David W Polly; Manish K Kasliwal; Paul A Broadstone; Steven D Glassman; Alexander R Vaccaro; Christopher P Ames; Christopher I Shaffrey
Journal:  Spine (Phila Pa 1976)       Date:  2012-11-01       Impact factor: 3.468

8.  The incidence and mortality of thromboembolic events in lumbar spine surgery.

Authors:  Steven J Fineberg; Matthew Oglesby; Alpesh A Patel; Miguel A Pelton; Kern Singh
Journal:  Spine (Phila Pa 1976)       Date:  2013-06-01       Impact factor: 3.468

9.  How do physicians talk with their patients about risks?

Authors:  A Kalet; J C Roberts; R Fletcher
Journal:  J Gen Intern Med       Date:  1994-07       Impact factor: 5.128

10.  Incidence and mortality of cardiac events in lumbar spine surgery.

Authors:  Steven J Fineberg; Kasra Ahmadinia; Alpesh A Patel; Matthew Oglesby; Kern Singh
Journal:  Spine (Phila Pa 1976)       Date:  2013-07-15       Impact factor: 3.468

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  1 in total

1.  Impact of socio-economic factors on radiation treatment after resection of metastatic brain tumors: trends from a private insurance database.

Authors:  David Y A Dadey; Adrian Rodrigues; Ghani Haider; Erqi L Pollom; John R Adler; Anand Veeravagu
Journal:  J Neurooncol       Date:  2022-05-21       Impact factor: 4.130

  1 in total

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