Damith T Woods1,2, Anthony C Kneebone2. 1. Faculty of Psychology, Cognition and Cognitive Neuroscience Laboratory Chulalongkorn University Bangkok Thailand. 2. Flinders Medical Center Department of Clinical Neuropsychology South Australia Australia.
Abstract
BACKGROUND: The purpose of this study was to examine differences in patient and caregiver ratings of memory function in a community sample of patients with Parkinson's disease (PD) diagnosed with and without mild cognitive impairment (PD-MCI). METHODS: One hundred sixty-five patient-caregiver pairings participated in the study. Patients with PD were administered a battery of neuropsychological tests assessing five of the key cognitive domains as indicated in the PD-MCI Movement Disorders Task Force criteria. Patients and caregivers also completed the Memory Assessment Clinics Self-Rating or Family Scale (MAC-S/MAC-F), and patients were divided into two groups, those with PD-MCI and those without. RESULTS: For patients diagnosed with PD-MCI, both patients and caregivers reported significantly more memory changes compared with patients without PD-MCI on the MAC-S and MAC-F. In contrast, for patients without PD-MCI, patients and caregivers differed significantly in their reporting of memory changes, with scores indicating that patients without PD-MCI felt their memory functioning was worse than what caregivers were reporting. CONCLUSIONS: Patients with PD without MCI might be more sensitive to memory changes than their caregivers. Whether the self-appraisal of memory problems is predictive of future cognitive difficulties, including progression to PD-MCI or PD dementia, should be the focus of future research.
BACKGROUND: The purpose of this study was to examine differences in patient and caregiver ratings of memory function in a community sample of patients with Parkinson's disease (PD) diagnosed with and without mild cognitive impairment (PD-MCI). METHODS: One hundred sixty-five patient-caregiver pairings participated in the study. Patients with PD were administered a battery of neuropsychological tests assessing five of the key cognitive domains as indicated in the PD-MCI Movement Disorders Task Force criteria. Patients and caregivers also completed the Memory Assessment Clinics Self-Rating or Family Scale (MAC-S/MAC-F), and patients were divided into two groups, those with PD-MCI and those without. RESULTS: For patients diagnosed with PD-MCI, both patients and caregivers reported significantly more memory changes compared with patients without PD-MCI on the MAC-S and MAC-F. In contrast, for patients without PD-MCI, patients and caregivers differed significantly in their reporting of memory changes, with scores indicating that patients without PD-MCI felt their memory functioning was worse than what caregivers were reporting. CONCLUSIONS: Patients with PD without MCI might be more sensitive to memory changes than their caregivers. Whether the self-appraisal of memory problems is predictive of future cognitive difficulties, including progression to PD-MCI or PD dementia, should be the focus of future research.
Authors: M H Tabert; S M Albert; L Borukhova-Milov; Y Camacho; G Pelton; X Liu; Y Stern; D P Devanand Journal: Neurology Date: 2002-03-12 Impact factor: 9.910
Authors: D Aarsland; K Bronnick; C Williams-Gray; D Weintraub; K Marder; J Kulisevsky; D Burn; P Barone; J Pagonabarraga; L Allcock; G Santangelo; T Foltynie; C Janvin; J P Larsen; R A Barker; M Emre Journal: Neurology Date: 2010-09-21 Impact factor: 9.910