| Literature DB >> 16024400 |
Pauline Aalten1, Evelien van Valen, Linda Clare, Geraldine Kenny, Frans Verhey.
Abstract
This article provides a review of the literature on clinical correlates of awareness in dementia. Most inconsistencies were found with regard to an association between depression and higher levels of awareness. Dysthymia, but not major depression, is probably related to higher levels of awareness. Anxiety also appears to be related to higher levels of awareness. Apathy and psychosis are frequently present in patients with less awareness, and may share common neuropathological substrates with awareness. Furthermore, unawareness seems to be related to difficulties in daily life functioning, increased caregiver burden, and deterioration in global dementia severity. Factors that may be of influence on the inconclusive data are discussed, as are future directions of research.Entities:
Mesh:
Year: 2005 PMID: 16024400 DOI: 10.1080/13607860500143075
Source DB: PubMed Journal: Aging Ment Health ISSN: 1360-7863 Impact factor: 3.658