| Literature DB >> 30357700 |
Shiplu Roy Chowdhury1, Mohd Fauzi Mh Busra1, Yogeswaran Lokanathan1, Min Hwei Ng1, Jia Xian Law1, Ude Chinedu Cletus2, Ruszymah Binti Haji Idrus3.
Abstract
Collagen type I is the most abundant matrix protein in the human body and is highly demanded in tissue engineering, regenerative medicine, and pharmaceutical applications. To meet the uprising demand in biomedical applications, collagen type I has been isolated from mammalians (bovine, porcine, goat and rat) and non-mammalians (fish, amphibian, and sea plant) source using various extraction techniques. Recent advancement enables fabrication of collagen scaffolds in multiple forms such as film, sponge, and hydrogel, with or without other biomaterials. The scaffolds are extensively used to develop tissue substitutes in regenerating or repairing diseased or damaged tissues. The 3D scaffolds are also used to develop in vitro model and as a vehicle for delivering drugs or active compounds.Entities:
Keywords: Biomaterial; Collagen type I; Drug delivery system; Fabrication; In vitro model; Tissue engineering; Tissue substitutes
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Year: 2018 PMID： 30357700 DOI： 10.1007/978-981-13-0947-2_21
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622