| Literature DB >> 3035380 |
M Chow, J F Newman, D Filman, J M Hogle, D J Rowlands, F Brown.
Abstract
We have obtained evidence that poliovirus and other picornavirus particles are specifically modified by having myristic acid covalently bound to a capsid protein. The electron density map of poliovirus confirms the position of the myristate molecule and defines its location in the virus particle. Analogies with other myristylated proteins suggest that the myristate moiety in picornaviruses may be involved in capsid assembly or in the entry of virus into cells.Entities:
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Year: 1987 PMID： 3035380 DOI： 10.1038/327482a0
Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962