Amir Humza Sohail1, Mohammed Sachal2, Muhammad Arslan Arif Maan3, Muhammad Soban3, Muhammad Salman Khan4, Muhammad Ehsan Bari5. 1. Medical College, Aga Khan University, Stadium Road, Karachi, Pakistan. ameer.hamzasohail@gmail.com. 2. King Edward Medical University, Lahore, Pakistan. 3. Medical College, Aga Khan University, Stadium Road, Karachi, Pakistan. 4. Department of Radiology, Aga Khan University, Karachi, Pakistan. 5. Department of Neurosurgery, Aga Khan University, Karachi, Pakistan.
Abstract
INTRODUCTION: Common sites of occurrence of extraosseous Ewing's sarcoma include the soft tissues and bones of the lower extremity, 12 paravertebral, and retroperitoneal regions. Primary intracranial Ewing's sarcoma/pPNET is usually intraparenchymal located 13 when supratentorially, and an extraaxial epidural tumor radiographically mimicking a meningioma is extremely rare. CASE PRESENTATION: A 20-year14 old male presented to the emergency department with a 1-day history of drowsiness, headache, and fever. Neurological exam15 ination revealed decreased muscle strength (4/5) in the left lower limb. Head computed tomography scan showed an epidural 16 space-occupying lesion in the right temporoparietal region, which was assumed to be a meningioma by radiographic criteria. However, the surgical specimen was diagnosed as Ewing's sarcoma. CONCLUSION: Primary intracranial extraosseous Ewing's sarcoma is a rare condition that may mimic a meningioma on imaging. Physicians must be cognizant of this possibility, particularly in any young individual with a solitary contrast-enhancing dural-based lesion.
INTRODUCTION: Common sites of occurrence of extraosseous Ewing's sarcoma include the soft tissues and bones of the lower extremity, 12 paravertebral, and retroperitoneal regions. Primary intracranial Ewing's sarcoma/pPNET is usually intraparenchymal located 13 when supratentorially, and an extraaxial epidural tumor radiographically mimicking a meningioma is extremely rare. CASE PRESENTATION: A 20-year14 old male presented to the emergency department with a 1-day history of drowsiness, headache, and fever. Neurological exam15 ination revealed decreased muscle strength (4/5) in the left lower limb. Head computed tomography scan showed an epidural 16 space-occupying lesion in the right temporoparietal region, which was assumed to be a meningioma by radiographic criteria. However, the surgical specimen was diagnosed as Ewing's sarcoma. CONCLUSION:Primary intracranial extraosseous Ewing's sarcoma is a rare condition that may mimic a meningioma on imaging. Physicians must be cognizant of this possibility, particularly in any young individual with a solitary contrast-enhancing dural-based lesion.
Authors: Franceska Dedeurwaerdere; Caterina Giannini; Raf Sciot; Brian P Rubin; Giorgio Perilongo; Laura Borghi; Maria Luisa Ballotta; Erwin Cornips; Anouk Demunter; Brigitte Maes; Angelo P Dei Tos Journal: Mod Pathol Date: 2002-06 Impact factor: 7.842