| Literature DB >> 30332627 |
Gerlanda Vella1, Gabriele Bergers2.
Abstract
Glioblastoma are highly immunosuppressive brain tumors that are known for their T cell paucity. In a recent issue of Nature Medicine, Chongsathidkiet et al. (2018) discovered a brain-specific mechanism of tumors to escape immunosurveillance by trapping T cells in the bone marrow through the loss of sphingosine-1-phosphate (S1P) receptor on the T cell surface.Entities:
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Year: 2018 PMID: 30332627 PMCID: PMC6589439 DOI: 10.1016/j.immuni.2018.10.006
Source DB: PubMed Journal: Immunity ISSN: 1074-7613 Impact factor: 31.745