Literature DB >> 30332627

Where Have All the T Cells Gone?

Gerlanda Vella1, Gabriele Bergers2.   

Abstract

Glioblastoma are highly immunosuppressive brain tumors that are known for their T cell paucity. In a recent issue of Nature Medicine, Chongsathidkiet et al. (2018) discovered a brain-specific mechanism of tumors to escape immunosurveillance by trapping T cells in the bone marrow through the loss of sphingosine-1-phosphate (S1P) receptor on the T cell surface.
Copyright © 2018. Published by Elsevier Inc.

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Year:  2018        PMID: 30332627      PMCID: PMC6589439          DOI: 10.1016/j.immuni.2018.10.006

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  8 in total

Review 1.  Sphingosine 1-phosphate signaling impacts lymphocyte migration, inflammation and infection.

Authors:  Irina V Tiper; James E East; Priyanka B Subrahmanyam; Tonya J Webb
Journal:  Pathog Dis       Date:  2016-06-27       Impact factor: 3.166

Review 2.  Sphingosine-1-phosphate receptor 1 signalling in T cells: trafficking and beyond.

Authors:  Christopher S Garris; Victoria A Blaho; Timothy Hla; May H Han
Journal:  Immunology       Date:  2014-07       Impact factor: 7.397

3.  Sphingosine 1-phosphate receptor type 1 regulates egress of mature T cells from mouse bone marrow.

Authors:  Yasuhiro Maeda; Noriyasu Seki; Noriko Sato; Kunio Sugahara; Kenji Chiba
Journal:  Int Immunol       Date:  2010-05-23       Impact factor: 4.823

Review 4.  T Cell Dysfunction in Cancer.

Authors:  Daniela S Thommen; Ton N Schumacher
Journal:  Cancer Cell       Date:  2018-04-09       Impact factor: 31.743

Review 5.  Current state of immunotherapy for glioblastoma.

Authors:  Michael Lim; Yuanxuan Xia; Chetan Bettegowda; Michael Weller
Journal:  Nat Rev Clin Oncol       Date:  2018-07       Impact factor: 66.675

6.  Systemic Tolerance Mediated by Melanoma Brain Tumors Is Reversible by Radiotherapy and Vaccination.

Authors:  Christopher M Jackson; Christina M Kochel; Christopher J Nirschl; Nicholas M Durham; Jacob Ruzevick; Angela Alme; Brian J Francica; Jimmy Elias; Andrew Daniels; Thomas W Dubensky; Peter Lauer; Dirk G Brockstedt; Emily G Baxi; Peter A Calabresi; Janis M Taube; Carlos A Pardo; Henry Brem; Drew M Pardoll; Michael Lim; Charles G Drake
Journal:  Clin Cancer Res       Date:  2015-10-21       Impact factor: 12.531

Review 7.  4-1BB (CD137), an inducible costimulatory receptor, as a specific target for cancer therapy.

Authors:  Dass S Vinay; Byoung S Kwon
Journal:  BMB Rep       Date:  2014-03       Impact factor: 4.778

8.  Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors.

Authors:  Pakawat Chongsathidkiet; Christina Jackson; Shohei Koyama; Franziska Loebel; Xiuyu Cui; S Harrison Farber; Karolina Woroniecka; Aladine A Elsamadicy; Cosette A Dechant; Hanna R Kemeny; Luis Sanchez-Perez; Tooba A Cheema; Nicholas C Souders; James E Herndon; Jean-Valery Coumans; Jeffrey I Everitt; Brian V Nahed; John H Sampson; Michael D Gunn; Robert L Martuza; Glenn Dranoff; William T Curry; Peter E Fecci
Journal:  Nat Med       Date:  2018-08-13       Impact factor: 53.440

  8 in total
  3 in total

Review 1.  Brain tumors: Cancer stem-like cells interact with tumor microenvironment.

Authors:  Hai-Long Liu; Ya-Nan Wang; Shi-Yu Feng
Journal:  World J Stem Cells       Date:  2020-12-26       Impact factor: 5.326

Review 2.  Sphingosine-1-phosphate (S1P) receptors: Promising drug targets for treating bone-related diseases.

Authors:  Lincheng Zhang; Yutong Dong; Yiran Wang; Wenhui Hu; Shiwu Dong; Yueqi Chen
Journal:  J Cell Mol Med       Date:  2020-03-10       Impact factor: 5.310

Review 3.  Explicating the Pivotal Pathogenic, Diagnostic, and Therapeutic Biomarker Potentials of Myeloid-Derived Suppressor Cells in Glioblastoma.

Authors:  Seidu A Richard
Journal:  Dis Markers       Date:  2020-11-04       Impact factor: 3.434

  3 in total

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