Literature DB >> 30326545

Utilizing simulated errors in radiotherapy plans to quantify the effectiveness of the physics plan review.

Olga Gopan1, Wade P Smith1, Alexei Chvetsov1, Kristi Hendrickson1, Alan Kalet1, Minsun Kim1, Matthew Nyflot1, Mark Phillips1, Lori Young1, Avrey Novak1, Jing Zeng1, Eric Ford1.   

Abstract

PURPOSE: The review of a radiation therapy plan by a physicist prior to treatment is a standard tool for ensuring the quality of treatments. However, little is known about how well this task is performed in practice. The goal of this study is to present a novel method to measure the effectiveness of physics plan review by introducing simulated errors into computerized "mock" treatment charts and measuring the performance of plan review by physicists.
METHODS: We generated six simulated treatment charts containing multiple errors. To select errors, we compiled a list based on events from a departmental incident learning system and an international incident learning system (SAFRON). Seventeen errors with the highest scores for frequency and severity were included in the simulations included six mock treatment charts. Eight physicists reviewed the simulated charts as they would a normal pretreatment plan review, with each chart being reviewed by at least six physicists. There were 113 data points for evaluation. Observer bias was minimized using a simple error vs hidden error approach, using detectability scores for stratification. The confidence interval for the proportion of errors detected was computed using the Wilson score interval.
RESULTS: Simulated errors were detected in 67% of reviews [58-75%] (95% confidence interval [CI] in brackets). Of the errors included in the simulated plans, the following error scenarios had the highest detection rates: an incorrect isocenter in DRR (93% [70-99%]), a planned dose different from the prescribed dose (92% [67-99%]) and invalid QA (85% [58-96%]). Errors with low detection rates included incorrect CT dataset (0%, [0-39%]) and incorrect isocenter localization in planning system (38% [18-64%]). Detection rates of errors from simulated charts were compared against observed detection rates of errors from a departmental incident learning system.
CONCLUSIONS: It has been notoriously difficult to quantify error and safety performance in oncology. This study uses a novel technique of simulated errors to quantify performance and suggests that the pretreatment physics plan review identifies some errors with high fidelity while other errors are more challenging to detect. These data will guide future work on standardization and automation. The example process studied here was physics plan review, but this approach of simulated errors may be applied in other contexts as well and may also be useful for training and education purposes.
© 2018 American Association of Physicists in Medicine.

Keywords:  error detection; error simulation; patient safety; physics plan review; quality assurance

Mesh:

Year:  2018        PMID: 30326545     DOI: 10.1002/mp.13242

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  3 in total

1.  Automatic Verification of Beam Apertures for Cervical Cancer Radiation Therapy.

Authors:  Kelly Kisling; Carlos Cardenas; Brian M Anderson; Lifei Zhang; Anuja Jhingran; Hannah Simonds; Peter Balter; Rebecca M Howell; Kathleen Schmeler; Beth M Beadle; Laurence Court
Journal:  Pract Radiat Oncol       Date:  2020-05-23

2.  Development and validation of a checklist for use with automatically generated radiotherapy plans.

Authors:  Kelly A Nealon; Laurence E Court; Raphael J Douglas; Lifei Zhang; Eun Young Han
Journal:  J Appl Clin Med Phys       Date:  2022-06-30       Impact factor: 2.243

3.  Errors detected during physics plan review for external beam radiotherapy.

Authors:  Frank-André Siebert; Markus Hirt; Marc Delaperrière; Jürgen Dunst
Journal:  Phys Imaging Radiat Oncol       Date:  2022-09-17
  3 in total

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