| Literature DB >> 30317991 |
Siva K Korada1, Nagendra S Yarla2, Vijayendra Mishra1, Mohamed A Daim3,4, Bechan Sharma5, Ashraf Gm6, Reggi R7, Palmery M7, Ilaria Peluso8, Mohammad A Kamal6,9,10.
Abstract
Strain, dose, duration, validated clinical trial studies and scientific substantiation of health claims are needed in order to define a successful probiotic. In particular, the potency of probiotic differs from strain to strain. In this view, we aimed to know whether the single strain or multi-strain construct is more beneficial. We found that the studies were still under debate and mechanisms remain sometimes unclear. No conclusion can be made based on the strain experimentation. Safety data and significant statistical results for efficacy via well-controlled clinical trials are needed. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.Keywords: Probiotics; gut microbiota; health benefits; multiple probiotics; safety recommendation; single strain.
Mesh:
Year: 2018 PMID: 30317991 DOI: 10.2174/1381612824666181012124136
Source DB: PubMed Journal: Curr Pharm Des ISSN: 1381-6128 Impact factor: 3.116