| Literature DB >> 30310486 |
Dominik Wiedemann1, Thomas Haberl1, Julia Riebandt1, Paul Simon1, Günther Laufer1, Daniel Zimpfer1.
Abstract
End-stage heart failure represents a substantial worldwide problem for the healthcare system. Despite significant improvements (medical heart failure treatment, implantable cardioverters, cardiac resyschronisation devices), long-term survival and quality of life of these patients remains poor. Heart transplantation has been an effective therapy for terminal heart failure, but it remains limited by an increasing shortage of available donor organs along with strict criteria defining acceptable recipients. For the last 50 years, mechanical alternatives to support the circulation have been investigated; however, during the early years device development has been marked in general by slow progress. However, in the past two decades, the technology has evolved dramatically. The purpose of this review is to give a short summary on the evolution of ventricular assist device (VAD) therapy and to give perspectives for future treatment of heart failure.Entities:
Keywords: Ventricular assist device; heart failure; mechanical circulatory support
Year: 2014 PMID: 30310486 PMCID: PMC6159437 DOI: 10.15420/ecr.2014.9.1.54
Source DB: PubMed Journal: Eur Cardiol ISSN: 1758-3756