| Literature DB >> 30310453 |
Alda Huqi1, Giacinta Guarini1, Doralisa Morrone1, Mario Marzilli1.
Abstract
Following revascularisation the majority of patients obtain symptom relief and improved quality of life. However, myocardial ischaemia may recur or persist in a significant patient subset. Symptom recurrence is usually attributed to inaccurate evaluation of epicardial stenosis, incomplete revascularisation or stent failure and disease progression. However, technological advances with modern imaging and/or physiological evaluation of epicardial plaques have not solved this issue. Conversely, recent clinical studies have shown that abnormal coronary vasomotion and increased myocardial resistance are frequent determinants of post-percutaneous coronary intervention (PCI) myocardial ischaemia. Strategies to enhance prediction of post-PCI angina include proper selection of patients undergoing revascularisation, construction of clinical prediction models, and further invasive evaluation at the time of coronary angiography in those with high likelihood.Entities:
Keywords: Persistent angina; coronary artery disease; ischaemic heart disease; microvascular dysfunction; percutaneous coronary intervention
Year: 2016 PMID: 30310453 PMCID: PMC6159460 DOI: 10.15420/ecr.2016:27:2
Source DB: PubMed Journal: Eur Cardiol ISSN: 1758-3756