| Literature DB >> 30298990 |
Anna Cronström1, Håkan Nero2, Leif E Dahlberg3.
Abstract
OBJECTIVE: To examine patient willingness and a possible shift in willingness for surgery and to investigate factors associated with this shift, following participation in the digital nonsurgical osteoarthritis (OA) treatment program Joint Academy.Entities:
Year: 2019 PMID: 30298990 PMCID: PMC6771662 DOI: 10.1002/acr.23772
Source DB: PubMed Journal: Arthritis Care Res (Hoboken) ISSN: 2151-464X Impact factor: 4.794
Figure 1Flow chart of the inclusion process. OA = osteoarthritis.
Baseline characteristics of included participants (n = 458)a
| Characteristic | Values |
|---|---|
| Women, % | 67.8 |
| Age, years | 62 ± 5.6 |
| Body mass index, kg/m2 | 26.9 ± 4.9 |
| Working situation, % | |
| Working | 46.6 |
| Retired | 45.5 |
| Unemployed | 3.3 |
| Sick‐leave | 4.2 |
| OA medication last 6 months, % | 49.9 |
| Previous surgery to other joint, % | 13.3 |
| Pain location knee, % | 58.2 |
| Pain baseline | 5.6 ± 2.2 |
| Walking difficulties at baseline, % | 84.5 |
| 30CST baseline median (quartiles) | 10 (8–12) |
| EQ‐5D baseline score | 0.64 ± 0.2 |
| Fear of physical activity at baseline, % | 23.6 |
| Consider surgery at baseline, % | 23.2 |
| Compliance level in percentage | 78.2 ± 17.3 |
Values are the mean ± SD unless indicated otherwise. OA = osteoarthritis; 30CST = 30‐second chair stand test; EQ‐5D = EuroQol 5‐domain questionnaire.
Non‐normally distributed data.
Differences in baseline demographics, pain, and function between those participants who considered surgery at baseline and those who did not (n = 458)a
| Factor | Willing | Unwilling |
|
|---|---|---|---|
| Sex | |||
| Women | 60 (19.4) | 250 (80.6) | 0.005 |
| Men | 46 (31.1) | 102 (68.9) | – |
| Age, mean ± SD years | 61 ± 9.5 | 62 ± 9.6 | 0.154 |
| Body mass index, mean ± SD kg/m2 | 28 ± 5.7 | 26.5 ± 4.7 | 0.007 |
| Working situation (n = 423) | |||
| Working | 48 (22.4) | 166 (77.6) | 0.642 |
| Retired | 43 (20.6) | 166 (79.4) | – |
| OA medication last 6 months | |||
| Yes | 65 (28.5) | 173 (71.5) | 0.007 |
| No | 41 (17.8) | 189 (82.2) | – |
| Previous surgery | |||
| Yes | 22 (36.1) | 39 (63.9) | 0.005 |
| No | 84 (21.2) | 313 (78.9) | – |
| Pain location | |||
| Hip | 43 (22.5) | 148 (77.5) | 0.787 |
| Knee | 63 (23.6) | 204 (76.4) | – |
| Pain at baseline, mean ± SD | 6.8 ± 1.8 | 5.2 ± 2.1 | <0.001 |
| EQ‐5D score, mean ± SD | 0.54 ± 0.19 | 0.68 ± 0.12 | <0.001 |
| Baseline walking difficulties | |||
| Yes | 102 (26.4) | 205 (73.6) | <0.001 |
| No | 4 (5.6) | 67 (94.4) | – |
| Baseline 30CST, median (quartiles) | 10.0 (8–11) | 10.0 (8–12) | 0.02 |
| Fear of physical activity at baseline | 32 (29.4) | 77 (70.6) | 0.078 |
Values are the number (%) unless indicated otherwise. OA = osteoarthritis; EQ‐5D = EuroQol 5‐domain questionnaire; 30CST = 30‐second chair stand test.
Statistically significant by the chi‐square test.
Independent t‐test.
Statistically significant by independent t‐test.
Chi‐square test.
Non‐normally distributed data (n = 447).
Statistically significant by Wilcoxon signed rank test for non‐normally distributed data.
Differences in pain and function at 6 weeks from baseline willingness to consider surgerya
| Factor | Willing at baseline (n = 104) | Unwilling at baseline (n = 348) | ||||
|---|---|---|---|---|---|---|
| Willing at 6 weeks (n = 72) | Reconsidered at 6 weeks (n = 32) |
| Unwilling at 6 weeks (n = 327) | Reconsidered at 6 weeks (n = 21) |
| |
| Pain at 6 weeks | 5.8 ± 1.9 | 4.1 ± 2.4 | <0.001 | 3.6 ± 2.2 | 5.5 ± 2.2 | 0.001 |
| Change in pain, baseline to 6 weeks | –1.3 ± 1.9 | –2 ± 3.6 | 0.330 | –1.5 ± 2.2 | –0.5 ± 2.0 | 0.043 |
| EQ‐5D at 6 weeks | 0.55 ± 0.18 | 0.69 ± 0.18 | 0.001 | 0.72 ± 0.12 | 0.56 ± 0.16 | <0.001 |
| Change in EQ‐5D, baseline to 6 weeks | 0.05 ± 0.15 | 0.06 ± 0.12 | 0.806 | 0.04 ± 0.13 | –0.04 ± 0.13 | 0.011 |
| Walking difficulties at 6 weeks, % | ||||||
| Yes | 73.3 | 26.6 | 0.031 | 90.9 | 9.1 | 0.009 |
| No | 46.7 | 53.3 | – | 97.9 | 2.1 | – |
| Fear of physical activity at 6 weeks, % | ||||||
| Yes | 80.0 | 20 | 0.341 | 95.7 | 4.3 | 0.687 |
| No | 67.8 | 32.2 | – | 93.5 | 6.5 | – |
| 30CST at 6 weeks, median (quartiles) | 11 (9–15) | 12 (10–15) | 0.289 | 12 (10–16) | 12 (9–15) | 0.18 |
| Change in 30CST, baseline to 6 weeks | 1.9 ± 4.5 | 2.2 ± 3.5 | 0.755 | 2.2 ± 4.2 | 2.74 ± 4.9 | 0.602 |
Values are the mean ± SD unless indicated otherwise. EQ‐5D = EuroQol 5‐domain questionnaire; 30CST = 30‐second chair stand test.
Statistically significant by independent t‐test.
Independent t‐test.
Statistically significant by the chi‐square test.
Chi‐square test.
Non‐normally distributed data.
Wilcoxon signed rank test for non‐normally distributed data.
Factors associated with the shift in willingness to consider surgery after completion of the program, adjusted for age, sex, and body mass indexa
| Independent variable | Adjusted OR (95% CI) |
|
|---|---|---|
| Shift from willing to unwilling | ||
| Pain at 6 weeks (n = 104) | 0.67 (0.53–0.85) | <0.001 |
| EQ‐5D score at 6 weeks (n = 103) | 1.64 (1.17–2.30) | 0.004 |
| Shift from unwilling to willing | ||
| Pain at 6 weeks (n = 347) | 1.63 (1.27–2.08) | <0.001 |
| Pain change (n = 347) | 1.30 (1.07–1.48) | 0.009 |
| Walking difficulties at 6 weeks (n = 347) | 4.30 (1.24–14.94) | 0.022 |
| EQ‐5D score at 6 weeks (n = 343) | 0.51 (0.39–0.67) | <0.001 |
| EQ‐5D score change (n = 343) | 0.63 (0.44–0.88) | 0.007 |
The dependent variable is willingness to consider surgery after completion of the program (at 6 weeks). Number of participants who shifted from willing to unwilling: n = 32; number of participants who shifted from unwilling to willing: n = 21. OR = odds ratio; 95% CI = 95% confidence interval. For the purpose of regression the EuroQol 5‐domain questionnaire (EQ‐5D) score was multiplied by 10.
All P values are statistically significant.