Marcos Custódio1, Priscila Lie Tobouti2, Bruno Matuck2, Suzana C O M de Sousa2. 1. Oral and Maxillofacial Pathology Department, School of Dentistry-University of São Paulo, Av. Professor Lineu Prestes, 2227 Cidade Universitária, São Paulo, SP, 05508-000, Brazil. marcosjcustodio@usp.br. 2. Oral and Maxillofacial Pathology Department, School of Dentistry-University of São Paulo, Av. Professor Lineu Prestes, 2227 Cidade Universitária, São Paulo, SP, 05508-000, Brazil.
Abstract
PURPOSE: We aimed to compare the histomorphological features of oral lymphoepithelial cysts (OLC) in different locations of the oral cavity and to verify the association between oral lymphoepithelial cysts and subgemmal neurogenous plaque (SNP) on biopsies from the lateral border of the tongue. METHODS: All cases diagnosed as OLC from the Oral Pathology Service at the School of Dentistry/University of São Paulo were retrieved. For all the cysts located in the tongue, their association to SNP was analyzed. Immunohistochemical staining against S100 was performed to confirm the diagnosis of SNP. RESULTS: Thirty-one cases were selected for morphological analysis and SNP was identified in 40% of cases, all of them positive for S100. In these cases, macroscopic analysis demonstrated two independent fragments. Microscopic analysis showed that cysts located in the floor of the mouth and ventral surface of the tongue showed less intense exocytosis, less formation of lymphoid follicles, and predominantly a moderate inflammatory infiltrate. CONCLUSIONS: OLC have a similar histological pattern regardless the location within the oral cavity and. In some cases, the biopsy specimen may be accompanied by a SNP as an adjacent independent structure.
PURPOSE: We aimed to compare the histomorphological features of oral lymphoepithelial cysts (OLC) in different locations of the oral cavity and to verify the association between oral lymphoepithelial cysts and subgemmal neurogenous plaque (SNP) on biopsies from the lateral border of the tongue. METHODS: All cases diagnosed as OLC from the Oral Pathology Service at the School of Dentistry/University of São Paulo were retrieved. For all the cysts located in the tongue, their association to SNP was analyzed. Immunohistochemical staining against S100 was performed to confirm the diagnosis of SNP. RESULTS: Thirty-one cases were selected for morphological analysis and SNP was identified in 40% of cases, all of them positive for S100. In these cases, macroscopic analysis demonstrated two independent fragments. Microscopic analysis showed that cysts located in the floor of the mouth and ventral surface of the tongue showed less intense exocytosis, less formation of lymphoid follicles, and predominantly a moderate inflammatory infiltrate. CONCLUSIONS: OLC have a similar histological pattern regardless the location within the oral cavity and. In some cases, the biopsy specimen may be accompanied by a SNP as an adjacent independent structure.
Authors: Ana Carolina Amorim Pellicioli; Felipe Paiva Fonseca; Rodrigo Neves Silva; Luiz Alcino Monteiro Gueiros; Oslei Paes de Almeida; Pablo Agustin Vargas; Marcio Ajudarte Lopes; Helder Antonio Rebelo Pontes; Manoela Domingues Martins; Vinícius Coelho Carrard; Alan Roger Santos-Silva Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Date: 2017-01-09
Authors: John Lennon Silva Cunha; Ana Luiza Oliveira Corrêa Roza; Vitória Maria Sousa Cruz; Jaqueline Lemes Ribeiro; Israel Leal Cavalcante; Roberta Barroso Cavalcante; Ana Lia Anbinder; Aline Corrêa Abrahão; Bruno Augusto Benevenuto de Andrade; Mário José Romañach; Fábio Ramôa Pires; Alan Roger Dos Santos-Silva; Márcio Ajudarte Lopes; Pablo Agustin Vargas; Ciro Dantas Soares; Oslei Paes de Almeida Journal: Head Neck Pathol Date: 2021-06-29