Literature DB >> 30292303

Recent advances in the applications of metabolomics in eye research.

Liyan Chen1, Yan Gao1, Louis Zizhao Wang2, Ning Cheung3, Gavin S W Tan3, Gemmy Chiu Ming Cheung3, Roger W Beuerman4, Tien Yin Wong5, Eric Chun Yong Chan6, Lei Zhou7.   

Abstract

Metabolomics, the identification and quantitation of metabolites in a system, have been applied to identify new biomarkers or elucidate disease mechanism. In this review, we discussed the application of metabolomics in several ocular diseases and recent developments in metabolomics regarding tear fluids analysis, data acquisition and processing.
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Eye disease; LC-MS/MS; Metabolite; Metabolomics; NMR

Mesh：

Year:  2018        PMID： 30292303     DOI： 10.1016/j.aca.2018.01.060

Source DB:  PubMed          Journal:  Anal Chim Acta        ISSN： 0003-2670            Impact factor:   6.558


  4 in total

1.  The profile of gut microbiota and central carbon-related metabolites in primary angle-closure glaucoma patients.

Authors:  Haijun Gong; Rui Zeng; Qiguan Li; Yao Liu; Chengguo Zuo; Jiawei Ren; Ling Zhao; Mingkai Lin
Journal:  Int Ophthalmol       Date:  2022-02-11       Impact factor: 2.031

2.  Serum metabolic signatures of high myopia among older Chinese adults.

Authors:  Chaofu Ke; Hua Xu; Qin Chen; Hua Zhong; Chen-Wei Pan
Journal:  Eye (Lond)       Date:  2020-05-18       Impact factor: 3.775

3.  1H-NMR analysis of amino acid metabolism in aqueous humor of patients with cataract, according to diabetes status.

Authors:  Jing Jin; Qian Sun; Zan Wu; Kun Liu; Zhengyu Song; Li Su
Journal:  J Int Med Res       Date:  2020-06       Impact factor: 1.671

4.  Metabolomic Alterations in the Tear Fluids of Patients With Superior Limbic Keratoconjunctivitis.

Authors:  Yan Zong; Chao Cheng; Kunke Li; Ran Xue; Ziyan Chen; Xiuping Liu; Kaili Wu
Journal:  Front Med (Lausanne)       Date:  2022-01-18
  4 in total

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