Literature DB >> 30291147

Technobiology's Enabler: The Magnetoelectric Nanoparticle.

Sakhrat Khizroev1.   

Abstract

To enable patient- and disease-specific diagnostic and treatment at the intracellular level in real time, it is imperative to engineer a perfect way to locally stimulate selected individual neurons, navigate and dispense a cargo of biomolecules into damaged cells or image sites with relatively high efficacy and with adequate spatial and temporal resolutions. Significant progress has been made using biotechnology; especially with the development of bioinformatics, there are endless molecular databases to identify biomolecules to target almost any disease-specific biomarker. Conversely, the technobiology approach that exploits advanced engineering to control underlying molecular mechanisms to recover biosystem's energy states at the molecular level as well as at the level of the entire network of cells (i.e., the internet of the human body) is still in its early research stage. The recently developed magnetoelectric nanoparticles (MENPs) provide a tool to enable the unique capabilities of technobiology. Using exemplary studies that could potentially lead to future pinpoint treatment and prevention of cancer, neurodegenerative diseases, and HIV, this article discusses how MENPs could become a vital enabling tool of technobiology.
Copyright © 2019 Cold Spring Harbor Laboratory Press; all rights reserved.

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Year:  2019        PMID: 30291147      PMCID: PMC6671931          DOI: 10.1101/cshperspect.a034207

Source DB:  PubMed          Journal:  Cold Spring Harb Perspect Med        ISSN: 2157-1422            Impact factor:   6.915


  39 in total

1.  Functional anatomy of human procedural learning determined with regional cerebral blood flow and PET.

Authors:  S T Grafton; J C Mazziotta; S Presty; K J Friston; R S Frackowiak; M E Phelps
Journal:  J Neurosci       Date:  1992-07       Impact factor: 6.167

Review 2.  Biodegradable, polymeric nanoparticle delivery systems for cancer therapy.

Authors:  Eric M Pridgen; Robert Langer; Omid C Farokhzad
Journal:  Nanomedicine (Lond)       Date:  2007-10       Impact factor: 5.307

Review 3.  Technology insight: noninvasive brain stimulation in neurology-perspectives on the therapeutic potential of rTMS and tDCS.

Authors:  Felipe Fregni; Alvaro Pascual-Leone
Journal:  Nat Clin Pract Neurol       Date:  2007-07

4.  Physical principles for scalable neural recording.

Authors:  Adam H Marblestone; Bradley M Zamft; Yael G Maguire; Mikhail G Shapiro; Thaddeus R Cybulski; Joshua I Glaser; Dario Amodei; P Benjamin Stranges; Reza Kalhor; David A Dalrymple; Dongjin Seo; Elad Alon; Michel M Maharbiz; Jose M Carmena; Jan M Rabaey; Edward S Boyden; George M Church; Konrad P Kording
Journal:  Front Comput Neurosci       Date:  2013-10-21       Impact factor: 2.380

Review 5.  Cell-mediated drug delivery.

Authors:  Elena V Batrakova; Howard E Gendelman; Alexander V Kabanov
Journal:  Expert Opin Drug Deliv       Date:  2011-02-24       Impact factor: 6.648

Review 6.  Tissue models for RF exposure evaluation at frequencies above 6 GHz.

Authors:  Marvin C Ziskin; Stanislav I Alekseev; Kenneth R Foster; Quirino Balzano
Journal:  Bioelectromagnetics       Date:  2018-02-08       Impact factor: 2.010

Review 7.  Neuronal activities underlying the electroencephalogram and evoked potentials of sleeping and waking: implications for information processing.

Authors:  A M Coenen
Journal:  Neurosci Biobehav Rev       Date:  1995       Impact factor: 8.989

8.  Targeted and controlled anticancer drug delivery and release with magnetoelectric nanoparticles.

Authors:  Alexandra Rodzinski; Rakesh Guduru; Ping Liang; Ali Hadjikhani; Tiffanie Stewart; Emmanuel Stimphil; Carolyn Runowicz; Richard Cote; Norman Altman; Ram Datar; Sakhrat Khizroev
Journal:  Sci Rep       Date:  2016-02-15       Impact factor: 4.379

9.  Multiferroic coreshell magnetoelectric nanoparticles as NMR sensitive nanoprobes for cancer cell detection.

Authors:  Abhignyan Nagesetti; Alexandra Rodzinski; Emmanuel Stimphil; Tiffanie Stewart; Chooda Khanal; Ping Wang; Rakesh Guduru; Ping Liang; Irina Agoulnik; Jeffrey Horstmyer; Sakhrat Khizroev
Journal:  Sci Rep       Date:  2017-05-03       Impact factor: 4.379

10.  Engineering optical mode ferromagnetic resonance in FeCoB films with ultrathin Ru insertion.

Authors:  Shandong Li; Cuiling Wang; Xian-Ming Chu; Guo-Xing Miao; Qian Xue; Wenqin Zou; Meimei Liu; Jie Xu; Qiang Li; Youyong Dai; Shishen Yan; Shishou Kang; Yunze Long; Yueguang Lü
Journal:  Sci Rep       Date:  2016-09-15       Impact factor: 4.379

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  1 in total

Review 1.  A Review of Piezoelectric and Magnetostrictive Biosensor Materials for Detection of COVID-19 and Other Viruses.

Authors:  Fumio Narita; Zhenjin Wang; Hiroki Kurita; Zhen Li; Yu Shi; Yu Jia; Constantinos Soutis
Journal:  Adv Mater       Date:  2020-11-24       Impact factor: 32.086

  1 in total

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