Literature DB >> 30288497

Impact of The Method of Diagnosis on The Stage of Breast Carcinoma.

Aylin Erdim1, Gülce Kayıkçı2, Selin Doğu2, Derya Zıvalı2, Gizem Pehlivan2, A Özdemir Aktan1.   

Abstract

OBJECTIVE: Screening mammography is recommended to women at a certain age to achieve an early diagnosis. The purpose of this study is to find out how breast carcinoma was diagnosed and the impact of the method of diagnosis on the stage of the tumor.
MATERIALS AND METHODS: In this study, 903 operated breast cancer patients, between 2010-2016, in a large volume Marmara University Istanbul Pendik Education and Research Hospital were analyzed retrospectively. Patients presenting with clinical symptoms and those diagnosed with screening were investigated separately. The percentage of the patients diagnosed with symptoms and the impact of the method of diagnosis on the stage of the tumor was the primary outcome of the study.
RESULTS: 738 patients fulfilling inclusion criteria with complete clinical records were analyzed. 126 patients (17%) were in the age range of 19-39 years, while 32% (236 patients) were 40-50 and 51% (376 patients) were older than 50 years.485 patients (65.7%) were diagnosed with a mass in the breast, while 241 (32.6%) patients were diagnosed with screening with mammography. Twelve patients (1.7%) presented with nipple discharge. Median tumor sizes measured in the resected specimen were 22 mm, 21 mm, and 21 mm in patients diagnosed with a mass, screening, and nipple discharge respectively. The difference among the groups were not significant (p=0.460).Axillary lymph nodes were positive in 210 (43.3%) of patients presenting with a mass in the breast while 85 patients (35.3%) diagnosed with screening had metastatic lymph nodes in the axilla. Three patients presenting with nipple discharge had positive axillary lymph nodes (p=0.137).
CONCLUSION: This study demonstrated that breast cancer screening programs in Turkey needs improvement and at the same time shows that screening with mammography after 40 years of age should be done annually despite Ministry of Health recommendations.

Entities:  

Keywords:  Patient; breast cancer; discharge; mass; screening

Year:  2018        PMID: 30288497      PMCID: PMC6170021          DOI: 10.5152/ejbh.2018.3870

Source DB:  PubMed          Journal:  Eur J Breast Health


  12 in total

1.  The Swedish Two-County Trial twenty years later. Updated mortality results and new insights from long-term follow-up.

Authors:  L Tabár; B Vitak; H H Chen; S W Duffy; M F Yen; C F Chiang; U B Krusemo; T Tot; R A Smith
Journal:  Radiol Clin North Am       Date:  2000-07       Impact factor: 2.303

2.  Comparing health system performance in OECD countries. Organization for Economic Cooperation and Development.

Authors:  G Anderson; P S Hussey
Journal:  Health Aff (Millwood)       Date:  2001 May-Jun       Impact factor: 6.301

3.  Changes in primary care provision in Turkey: A comparison of 1993 and 2012.

Authors:  Mehmet Akman; Sibel Sakarya; Mehmet Sargın; İlhami Ünlüoğlu; Memet Taşkın Eğici; Wienke G W Boerma; Willemijn L A Schäfer
Journal:  Health Policy       Date:  2016-12-05       Impact factor: 2.980

4.  Breast-Cancer Tumor Size, Overdiagnosis, and Mammography Screening Effectiveness.

Authors:  H Gilbert Welch; Philip C Prorok; A James O'Malley; Barnett S Kramer
Journal:  N Engl J Med       Date:  2016-10-13       Impact factor: 91.245

5.  Cancer Statistics, 2017.

Authors:  Rebecca L Siegel; Kimberly D Miller; Ahmedin Jemal
Journal:  CA Cancer J Clin       Date:  2017-01-05       Impact factor: 508.702

6.  Emerging Concepts in Breast Cancer Risk Prediction.

Authors:  Gretchen L Gierach; Xiaohong R Yang; Jonine D Figueroa; Mark E Sherman
Journal:  Curr Obstet Gynecol Rep       Date:  2013-03

7.  Cost-Effectiveness of Breast Cancer Screening in Turkey, a Developing Country: Results from Bahçeşehir Mammography Screening Project.

Authors:  Vahit Özmen; Sibel Ö Gürdal; Neslihan Cabioğlu; Beyza Özcinar; A Nilüfer Özaydın; Arda Kayhan; Erkin Arıbal; Cennet Sahin; Pınar Saip; Oğuzhan Alagöz
Journal:  Eur J Breast Health       Date:  2017-07-01

8.  Effect of three decades of screening mammography on breast-cancer incidence.

Authors:  Archie Bleyer; H Gilbert Welch
Journal:  N Engl J Med       Date:  2012-11-22       Impact factor: 91.245

9.  Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012.

Authors:  Jacques Ferlay; Isabelle Soerjomataram; Rajesh Dikshit; Sultan Eser; Colin Mathers; Marise Rebelo; Donald Maxwell Parkin; David Forman; Freddie Bray
Journal:  Int J Cancer       Date:  2014-10-09       Impact factor: 7.396

Review 10.  Screening for breast cancer with mammography.

Authors:  Peter C Gøtzsche; Karsten Juhl Jørgensen
Journal:  Cochrane Database Syst Rev       Date:  2013-06-04
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