Mirinae Kim1, Rae Young Kim1, Young-Hoon Park1,2. 1. Department of Ophthalmology and Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. 2. Catholic Institute for Visual Science, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Abstract
Purpose: To assess choroidal thicknesses and choroidal vascularity index (CVI) in HLA-B27-associated uveitis. Methods: Medical records of 45 treatment-naive unilateral HLA-B27-associated uveitis patients presenting with first episode and with onset time of < 1-week were reviewed. Results: Mean choroidal thickness was 275.98 ± 71.62 in acute phase and 254.93 ± 73.48 after resolution (p = .003). Mean CVI was 34.75 ± 3.08 in acute phase and 33.56 ± 2.48 after resolution (p < .001). Interestingly, even in fellow eyes, there were relative retinal and choroidal thickening and relative choroidal vascular engorgement in acute phase, but these differences were not significant. Degree of anterior chamber inflammation was correlated with relative choroidal vascular engorgement (p = .001) and choroidal thickening (p = .044). Conclusion: Eyes with acute HLA-B27-associated uveitis exhibited choroidal thickening with increased choroidal vascularity that subsequently decreased after uveitis resolution. These were evident even in patients without posterior segment involvement.
Purpose: To assess choroidal thicknesses and choroidal vascularity index (CVI) in HLA-B27-associated uveitis. Methods: Medical records of 45 treatment-naive unilateral HLA-B27-associated uveitispatients presenting with first episode and with onset time of < 1-week were reviewed. Results: Mean choroidal thickness was 275.98 ± 71.62 in acute phase and 254.93 ± 73.48 after resolution (p = .003). Mean CVI was 34.75 ± 3.08 in acute phase and 33.56 ± 2.48 after resolution (p < .001). Interestingly, even in fellow eyes, there were relative retinal and choroidal thickening and relative choroidal vascular engorgement in acute phase, but these differences were not significant. Degree of anterior chamber inflammation was correlated with relative choroidal vascular engorgement (p = .001) and choroidal thickening (p = .044). Conclusion: Eyes with acute HLA-B27-associated uveitis exhibited choroidal thickening with increased choroidal vascularity that subsequently decreased after uveitis resolution. These were evident even in patients without posterior segment involvement.