Federico Coccolini1, Marco Ceresoli2, Yoram Kluger3, Andrew Kirkpatrick4, Giulia Montori5, Fracensco Salvetti6, Paola Fugazzola7, Matteo Tomasoni8, Massimo Sartelli9, Luca Ansaloni10, Fausto Catena11, Ionut Negoi12, Monica Zese13, Savino Occhionorelli13, Sergei Shlyapnikov14, Christian Galatioto15, Massimo Chiarugi15, Zaza Demetrashvili16, Daniele Dondossola17, Orestis Ioannidis18, Giuseppe Novelli19, Mirco Nacoti20, Desmond Khor21, Kenji Inaba21, Demetrios Demetriades21, Torsten Kaussen22, Asri Che Jusoh23, Wagih Ghannam24, Boris Sakakushev25, Ohad Guetta26, Agron Dogjani27, Stefano Costa28, Sandeep Singh29, Dimitrios Damaskos30, Arda Isik31, Kuo-Ching Yuan32, Francesco Trotta33, Stefano Rausei34, Aleix Martinez-Perez35, Giovanni Bellanova36, ViniciusCordeiro Fonseca37, Fernando Hernández38, Athanasios Marinis39, Wellington Fernandes40, Martha Quiodettis41, Miklosh Bala42, Andras Vereczkei43, Rafael Curado44, Gustavo Pereira Fraga44, Bruno M Pereira44, Mahir Gachabayov45, Guillermo Perez Chagerben46, Miguel Leon Arellano47, Sefa Ozyazici48, Gianluca Costa49, Tugan Tezcaner50, Matteo Porta51, Yousheng Li52, Faruk Karateke53, Dimitrios Manatakis54, Federico Mariani55, Federic Lora56, Ivan Sahderov57, Boyko Atanasov58, Sergio Zegarra59, Luca Gianotti60, Luca Fattori60, Rao Ivatury61. 1. General, Emergency and Trauma Surgery Dept., Bufalini Hospital, Cesena, Italy. Electronic address: Federico.coccolini@gmail.com. 2. General and Emergency Surgery, Milano-Bicocca University, School of Medicine and Surgery, Monza, Italy. Electronic address: Marco.ceresoli@libero.it. 3. Division of General Surgery Rambam Health Care Campus Haifa, Israel. Electronic address: y_kluger@rambam.health.gov.il. 4. Dept. of Surgery, Foothills Medical Centre, Calgary, Canada. Electronic address: Andrew.Kirkpatrick@albertahealthservices.ca. 5. General Surgery, San Giovanni Bianco Hospital, Bergamo, Italy. Electronic address: Giulia.montori@gmail.com. 6. General, Emergency and Trauma Surgery Dept., Bufalini Hospital, Cesena, Italy. Electronic address: francisalvetti@gmail.com. 7. General, Emergency and Trauma Surgery Dept., Bufalini Hospital, Cesena, Italy. Electronic address: paola.fugazzola@gmail.com. 8. General, Emergency and Trauma Surgery Dept., Bufalini Hospital, Cesena, Italy. Electronic address: matteo.tomasoni83@gmail.com. 9. General and Emergency Surgery, Macerata Hospital, Macerata, Italy. Electronic address: Massimosartelli@gmail.com. 10. General, Emergency and Trauma Surgery Dept., Bufalini Hospital, Cesena, Italy. Electronic address: Aiace63@gmail.com. 11. Emergency Surgery dept., Parma University Hospital, Parma, Italy. Electronic address: faustocatena@gmail.com. 12. Emergency Surgery Hospital, Bucharest, Romania. 13. Emergency Surgery dept. Ferrara University Hospital, Ferrara, Italy. 14. Science Research of Emergency Care N. A., Djanelidze, Russia. 15. Azienda Ospedaliera Universitaria Pisana, Pisa, Italy. 16. Kipshidze Central Universtity Hospital, Kipshidze, Georgia. 17. HPB Surgery, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Italy. 18. Fourth Surgical dept. Hospital George Papanikolau, Aristotle University, Thessaloniki, Greece. 19. General Surgery, Infermi Hospital, Rimini, Italy. 20. Pediatric Intensive Care Unit, Papa Giovanni XXIII Hospital, Bergamo, Italy. 21. LAS+USC Medical Centre, Los Angeles, California. 22. Pediatric Intensive Care Unit, Hannover University Hospital, Hannover, Germany. 23. KhualaKrai Hospital, Malaysia. 24. Mansoura Faculty of Medicine, Egypt. 25. Medical University of Plovdiv, Plovdiv, Bulgaria. 26. SorokaMedical Centre, Israel. 27. University Hospital of Trauma, Albania. 28. Emergency and General Surgery, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milano, Italy. 29. Oxford University Hospital, United Kindom. 30. John Radcliffe Hospital, Oxford. 31. Erzincan University Faculty Of Medicine MengucekGazi Training Research Hospital Erzincan, Turkey. 32. ChangGungMemorial Hospital, Taiwan. 33. Ospedale Maggiore, Lodi, Italy. 34. Ospedale di Circolo e Fondazione Macchi, University of Insubria, Varese, Italy. 35. Hospital Universitario DoctorPeset, Spain. 36. S.S. Annunziata Hospital, Taranto, Italy. 37. Hospital Santa Virgínia, São Paulo, Brazil. 38. Hospital Central Militar, Mexico. 39. Tzaneio General Hospital of Piraeus, Greece. 40. Hospital Regional de Sao Jose, Brazil. 41. Hospital Santo Tomás, Panama. 42. Hadassah Hebrew University Medical Center, Jerusalem, Israel. 43. Dept. of Surgery, Medical School University Pécs, Hungary. 44. Hospital De Clinicas Da Unicamp, Brazil. 45. Vladimir City Clinical Hospital of Emergency Medicine, Russia. 46. University Hospital, Ecuador. 47. Hospital La Paz, Spain. 48. Adana Numune Training and Research Hospital, Department of Surgery, Adana, Turkey. 49. Ospedale Sant'Andrea University Hospital Sapienza, Rome, Italy. 50. Baskent University School of Medicine, Turkey. 51. General Surgery, IRCCS Policlinico San Donato, Milano, Italy. 52. Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China. 53. Numune Training and Research Hospital, Department of Surgery, Numune, Turkey. 54. Department of Surgery, Athens Naval and Veterans Hospital, Athens, Greece. 55. General Surgery, Santa Maria alleScotteUniversitary Hospital Siena, Italy. 56. General Surgery, Cittàdella Salute e dellascienza, Torino, Italy. 57. General Surgery, Krasnoyarsk Regional Hospital, Krasnoyarsk, Russia. 58. General Surgery, UMHAT"Eurohospital" Plovdiv, Bulgaria. 59. General Surgery, Hospital Almenara, Lima, Peru. 60. General and Emergency Surgery, Milano-Bicocca University School of Medicine and surgery, Monza, Italy. 61. Virginia Commonwealth University, Richmond, Virginia, USA.
Abstract
INTRODUCTION: No definitive data describing associations between cases of Open Abdomen (OA) and Entero-atmospheric fistulae (EAF) exist. The World Society of Emergency Surgery (WSES) and the Panamerican Trauma Society (PTS) thus analyzed the International Register of Open Abdomen (IROA) to assess this question. MATERIAL AND METHODS: A prospective analysis of adult patients enrolled in the IROA. RESULTS: Among 649 adult patients with OA 58 (8.9%) developed EAF. Indications for OA were peritonitis (51.2%) and traumatic-injury (16.8%). The most frequently utilized temporary abdominal closure techniques were Commercial-NPWT (46.8%) and Bogotà-bag (21.9%). Mean OA days were 7.9 ± 18.22. Overall mortality rate was 29.7%, with EAF having no impact on mortality. Multivariate analysis associated cancer (p = 0.018), days of OA (p = 0.003) and time to provision-of-nutrition (p = 0.016) with EAF occurrence. CONCLUSION: Entero-atmospheric fistulas are influenced by the duration of open abdomen treatment and by the nutritional status of the patient. Peritonitis, intestinal anastomosis, negative pressure and oral or enteral nutrition were not risk factors for EAF during OA treatment.
INTRODUCTION: No definitive data describing associations between cases of Open Abdomen (OA) and Entero-atmospheric fistulae (EAF) exist. The World Society of Emergency Surgery (WSES) and the Panamerican Trauma Society (PTS) thus analyzed the International Register of Open Abdomen (IROA) to assess this question. MATERIAL AND METHODS: A prospective analysis of adult patients enrolled in the IROA. RESULTS: Among 649 adult patients with OA 58 (8.9%) developed EAF. Indications for OA were peritonitis (51.2%) and traumatic-injury (16.8%). The most frequently utilized temporary abdominal closure techniques were Commercial-NPWT (46.8%) and Bogotà-bag (21.9%). Mean OA days were 7.9 ± 18.22. Overall mortality rate was 29.7%, with EAF having no impact on mortality. Multivariate analysis associated cancer (p = 0.018), days of OA (p = 0.003) and time to provision-of-nutrition (p = 0.016) with EAF occurrence. CONCLUSION: Entero-atmospheric fistulas are influenced by the duration of open abdomen treatment and by the nutritional status of the patient. Peritonitis, intestinal anastomosis, negative pressure and oral or enteral nutrition were not risk factors for EAF during OA treatment.
Authors: Massimo Sartelli; Federico Coccolini; Yoram Kluger; Ervis Agastra; Fikri M Abu-Zidan; Ashraf El Sayed Abbas; Luca Ansaloni; Abdulrashid Kayode Adesunkanmi; Boyko Atanasov; Goran Augustin; Miklosh Bala; Oussama Baraket; Suman Baral; Walter L Biffl; Marja A Boermeester; Marco Ceresoli; Elisabetta Cerutti; Osvaldo Chiara; Enrico Cicuttin; Massimo Chiarugi; Raul Coimbra; Elif Colak; Daniela Corsi; Francesco Cortese; Yunfeng Cui; Dimitris Damaskos; Nicola De' Angelis; Samir Delibegovic; Zaza Demetrashvili; Belinda De Simone; Stijn W de Jonge; Sameer Dhingra; Stefano Di Bella; Francesco Di Marzo; Salomone Di Saverio; Agron Dogjani; Therese M Duane; Mushira Abdulaziz Enani; Paola Fugazzola; Joseph M Galante; Mahir Gachabayov; Wagih Ghnnam; George Gkiokas; Carlos Augusto Gomes; Ewen A Griffiths; Timothy C Hardcastle; Andreas Hecker; Torsten Herzog; Syed Mohammad Umar Kabir; Aleksandar Karamarkovic; Vladimir Khokha; Peter K Kim; Jae Il Kim; Andrew W Kirkpatrick; Victor Kong; Renol M Koshy; Igor A Kryvoruchko; Kenji Inaba; Arda Isik; Katia Iskandar; Rao Ivatury; Francesco M Labricciosa; Yeong Yeh Lee; Ari Leppäniemi; Andrey Litvin; Davide Luppi; Gustavo M Machain; Ronald V Maier; Athanasios Marinis; Cristina Marmorale; Sanjay Marwah; Cristian Mesina; Ernest E Moore; Frederick A Moore; Ionut Negoi; Iyiade Olaoye; Carlos A Ordoñez; Mouaqit Ouadii; Andrew B Peitzman; Gennaro Perrone; Manos Pikoulis; Tadeja Pintar; Giuseppe Pipitone; Mauro Podda; Kemal Raşa; Julival Ribeiro; Gabriel Rodrigues; Ines Rubio-Perez; Ibrahima Sall; Norio Sato; Robert G Sawyer; Helmut Segovia Lohse; Gabriele Sganga; Vishal G Shelat; Ian Stephens; Michael Sugrue; Antonio Tarasconi; Joel Noutakdie Tochie; Matti Tolonen; Gia Tomadze; Jan Ulrych; Andras Vereczkei; Bruno Viaggi; Chiara Gurioli; Claudio Casella; Leonardo Pagani; Gian Luca Baiocchi; Fausto Catena Journal: World J Emerg Surg Date: 2021-09-25 Impact factor: 5.469
Authors: Alexis Theodorou; Agnes Jedig; Steffen Manekeller; Arnulf Willms; Dimitrios Pantelis; Hanno Matthaei; Nico Schäfer; Jörg C Kalff; Martin W von Websky Journal: Front Surg Date: 2021-03-29
Authors: Elisabeth Gasser; Daniel Rezaie; Johanna Gius; Andreas Lorenz; Philipp Gehwolf; Alexander Perathoner; Dietmar Öfner; Reinhold Kafka-Ritsch Journal: Front Surg Date: 2021-06-04