Literature DB >> 30271671

Diabetes-Related Cognitive Decline, a Global Health Issue, and New Treatments Approaches.

Vera Novak1, Federico Gomez1, Alexandre Campos Dias1, Daniela A Pimentel2, Freddy J Alfaro1.   

Abstract

The epidemic of type 2 diabetes (T2DM) is spreading around the globe and challenging the unprecedented success of health sciences in increasing longevity. T2DM has been linked to accelerated brain aging, functional decline in older adults and dementia. Brain insulin resistance and glycemic variability are potential mechanisms underlying T2DM-related brain damage and cognitive decline. Intranasal insulin therapy has emerged as a potential new treatment for T2DM-related cognitive impairment. Wearable technologies now allow better monitoring of behaviors and glycemic levels over several days and deliver real time feedback that can be used to improve self-management and lead to new prevention strategies and therapies for T2DM complications.

Entities:  

Keywords:  Glycemic Variability; Intranasal Insulin; Type 2 Diabetes; Wearable Technology

Year:  2017        PMID: 30271671      PMCID: PMC6159895          DOI: 10.4018/IJPHIM.2017070104

Source DB:  PubMed          Journal:  Int J Priv Health Inf Manag        ISSN: 2155-5621


  31 in total

1.  Continuous glucose monitoring in people with diabetes: the randomized controlled Glucose Level Awareness in Diabetes Study (GLADIS).

Authors:  J P New; R Ajjan; A F H Pfeiffer; G Freckmann
Journal:  Diabet Med       Date:  2015-02-20       Impact factor: 4.359

2.  Intranasal insulin increases regional cerebral blood flow in the insular cortex in men independently of cortisol manipulation.

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Journal:  Hum Brain Mapp       Date:  2013-08-01       Impact factor: 5.038

3.  Diabetes mellitus and risk of dementia in the Kungsholmen project: a 6-year follow-up study.

Authors:  W L Xu; C X Qiu; A Wahlin; B Winblad; L Fratiglioni
Journal:  Neurology       Date:  2004-10-12       Impact factor: 9.910

4.  MOPET: a context-aware and user-adaptive wearable system for fitness training.

Authors:  Fabio Buttussi; Luca Chittaro
Journal:  Artif Intell Med       Date:  2008-01-30       Impact factor: 5.326

5.  Cognitive impairment: an increasingly important complication of type 2 diabetes: the age, gene/environment susceptibility--Reykjavik study.

Authors:  Jane S Saczynski; María K Jónsdóttir; Melissa E Garcia; Palmi V Jonsson; Rita Peila; Gudny Eiriksdottir; Elin Olafsdottir; Tamara B Harris; Vilmundur Gudnason; Lenore J Launer
Journal:  Am J Epidemiol       Date:  2008-10-03       Impact factor: 4.897

Review 6.  Do weight management interventions delivered by online social networks effectively improve body weight, body composition, and chronic disease risk factors? A systematic review.

Authors:  Erik A Willis; Amanda N Szabo-Reed; Lauren T Ptomey; Felicia L Steger; Jeffery J Honas; Richard A Washburn; Joseph E Donnelly
Journal:  J Telemed Telecare       Date:  2016-07-09       Impact factor: 6.184

Review 7.  Intranasal insulin to improve memory function in humans.

Authors:  Christian Benedict; Manfred Hallschmid; Bernd Schultes; Jan Born; Werner Kern
Journal:  Neuroendocrinology       Date:  2007-07-20       Impact factor: 4.914

Review 8.  Contributions of brain insulin resistance and deficiency in amyloid-related neurodegeneration in Alzheimer's disease.

Authors:  Suzanne M de la Monte
Journal:  Drugs       Date:  2012-01-01       Impact factor: 9.546

9.  Effectiveness of lifestyle interventions for individuals with severe obesity and type 2 diabetes: results from the Look AHEAD trial.

Authors:  Jessica L Unick; Daniel Beavers; John M Jakicic; Abbas E Kitabchi; William C Knowler; Thomas A Wadden; Rena R Wing
Journal:  Diabetes Care       Date:  2011-08-11       Impact factor: 19.112

10.  Using new technologies to promote weight management: a randomised controlled trial study protocol.

Authors:  Monica Jane; Jonathan Foster; Martin Hagger; Sebely Pal
Journal:  BMC Public Health       Date:  2015-05-27       Impact factor: 3.295

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  1 in total

1.  Presence of White Matter Lesions Associated with Diabetes-Associated Cognitive Decline in Male Rat Models of Pre-Type 2 Diabetes.

Authors:  Jun Li; Yafei Guo; Qingju Li; Keke Miao; Chongxian Wang; Dongming Zhang; Chenguang Tian; Suhe Zhang
Journal:  Med Sci Monit       Date:  2019-12-18
  1 in total

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