| Literature DB >> 3027135 |
P Morgan-Capner, J A Morris, M B McIllmurray, J A Thomas, D H Crawford, T Azim.
Abstract
A fatal case of infectious mononucleosis occurred in a young adult. Abnormal serological features were noted in his mother, although there was no other family history suggesting an inherited defect of immune response to Epstein-Barr virus (EBV). The cellular infiltrate observed in tissues obtained at necropsy was analysed with a range of specific monoclonal and polyclonal antibodies. Polyclonal plasmacytoid B cell proliferation had occurred in many tissues. These cells were positive for EBV nuclear antigen, but viral particles were not seen on ultrastructural examination, and the virus was not isolated, suggesting a non-permissive infection.Entities:
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Year: 1986 PMID: 3027135 PMCID: PMC1140795 DOI: 10.1136/jcp.39.12.1317
Source DB: PubMed Journal: J Clin Pathol ISSN: 0021-9746 Impact factor: 3.411