Literature DB >> 3027135

Immunohistological studies of lymphoproliferative lesions in a fatal case of Epstein-Barr virus infection.

P Morgan-Capner, J A Morris, M B McIllmurray, J A Thomas, D H Crawford, T Azim.   

Abstract

A fatal case of infectious mononucleosis occurred in a young adult. Abnormal serological features were noted in his mother, although there was no other family history suggesting an inherited defect of immune response to Epstein-Barr virus (EBV). The cellular infiltrate observed in tissues obtained at necropsy was analysed with a range of specific monoclonal and polyclonal antibodies. Polyclonal plasmacytoid B cell proliferation had occurred in many tissues. These cells were positive for EBV nuclear antigen, but viral particles were not seen on ultrastructural examination, and the virus was not isolated, suggesting a non-permissive infection.

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Year:  1986        PMID: 3027135      PMCID: PMC1140795          DOI: 10.1136/jcp.39.12.1317

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  14 in total

1.  A family study of the X-linked lymphoproliferative syndrome: evidence for a B cell defect contributing to the immunodeficiency.

Authors:  I Ando; G Morgan; R J Levinsky; D H Crawford
Journal:  Clin Exp Immunol       Date:  1986-02       Impact factor: 4.330

2.  Epstein-Barr-virus induced lymphoproliferation. Implications for antiviral chemotherapy.

Authors:  J L Sullivan; P Medveczky; S J Forman; S M Baker; J E Monroe; C Mulder
Journal:  N Engl J Med       Date:  1984-11-01       Impact factor: 91.245

3.  Epstein-Barr virus-induced B-cell lymphoma after renal transplantation: acyclovir therapy and transition from polyclonal to monoclonal B-cell proliferation.

Authors:  D W Hanto; G Frizzera; K J Gajl-Peczalska; K Sakamoto; D T Purtilo; H H Balfour; R L Simmons; J S Najarian
Journal:  N Engl J Med       Date:  1982-04-15       Impact factor: 91.245

4.  A monoclonal antibody (anti-Tac) reactive with activated and functionally mature human T cells. I. Production of anti-Tac monoclonal antibody and distribution of Tac (+) cells.

Authors:  T Uchiyama; S Broder; T A Waldmann
Journal:  J Immunol       Date:  1981-04       Impact factor: 5.422

5.  Diffuse polyclonal B-cell lymphoma during primary infection with Epstein-Barr virus.

Authors:  J E Robinson; N Brown; W Andiman; K Halliday; U Francke; M F Robert; M Andersson-Anvret; D Horstmann; G Miller
Journal:  N Engl J Med       Date:  1980-06-05       Impact factor: 91.245

6.  Phenotypic expression of B-lymphocytes. 1. Identification with monoclonal antibodies in normal lymphoid tissues.

Authors:  S M Hsu; E S Jaffe
Journal:  Am J Pathol       Date:  1984-03       Impact factor: 4.307

7.  Outbreak of Burkitt's-like lymphoma in homosexual men.

Authors:  J L Ziegler; W L Drew; R C Miner; L Mintz; E Rosenbaum; J Gershow; E T Lennette; J Greenspan; E Shillitoe; J Beckstead; C Casavant; K Yamamoto
Journal:  Lancet       Date:  1982-09-18       Impact factor: 79.321

8.  Lymphoproliferative disorders in cardiac transplant recipients are multiclonal lymphomas.

Authors:  M L Cleary; J Sklar
Journal:  Lancet       Date:  1984-09-01       Impact factor: 79.321

9.  HLA-DR-antigen-associated restriction of EBV-specific cytotoxic T-cell colonies.

Authors:  I S Misko; J H Pope; R Hütter; T D Soszynski; R G Kane
Journal:  Int J Cancer       Date:  1984-02-15       Impact factor: 7.396

10.  A monoclonal antibody that detects HLA-D region antigen in routinely fixed, wax embedded sections of normal and neoplastic lymphoid tissues.

Authors:  A A Epenetos; L G Bobrow; T E Adams; C M Collins; P G Isaacson; W F Bodmer
Journal:  J Clin Pathol       Date:  1985-01       Impact factor: 3.411

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