| Literature DB >> 6147550 |
Abstract
Tissue specimens from 5 immunosuppressed cardiac transplant recipients with lymphoproliferative disorders were examined for rearrangements in immunoglobulin DNA. In each case DNA analysis of tissues obtained from several sites or at various times showed different clonal immunoglobulin gene rearrangements for each of the three immunoglobulin gene loci. These findings indicate that lymphoproliferative disorders in immunosuppressed cardiac transplant recipients represent multiclonal or oligoclonal B cell lymphomas.Entities:
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Year: 1984 PMID: 6147550 DOI: 10.1016/s0140-6736(84)92566-2
Source DB: PubMed Journal: Lancet ISSN: 0140-6736 Impact factor: 79.321