| Literature DB >> 30270247 |
Zhoor Hamid1, Tassneem Hamid2, Khider Alsedig3, Tajeldin Abdallah4, Arwa Elaagip5, Ayman Ahmed2, Fatima Khalid6, Muzamil Abdel Hamid2.
Abstract
The tropical environment of Sudan promotes the spread of mosquito-transmitted diseases such as dengue virus (DENV) infection. The current understanding of the geographical distribution of DENV serotypes and genotypes in Sudan is limited. In this study, molecular techniques (reverse transcriptase [RT]-PCR and sequencing) followed by phylogenetic analysis were used to characterize DENV isolated from the blood samples of suspected dengue patients admitted to Kassala Hospital, Kassala state, Sudan, in 2016 and 2017. We identified DENV infection in 4 patients by RT-PCR. Phylogenetic analysis revealed that the isolated virus sequences belong to the Cosmopolitan genotype of DENV serotype 2. This is the first study to confirm the presence of DENV serotype 2 in Kassala state, Sudan. Our results indicate the need for wider investigations of the DENV serotype composition and studies to evaluate their contribution to ongoing transmission.Entities:
Keywords: DENV; Kassala; Sudan; genotype; serotype
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Year: 2018 PMID： 30270247 DOI： 10.7883/yoken.JJID.2018.267
Source DB: PubMed Journal: Jpn J Infect Dis ISSN： 1344-6304 Impact factor: 1.362