Hakan Hanımoğlu1, Serdar Çevik2, Hakan Yılmaz3, Atilla Kaplan3, Fatih Çalış4, Salim Katar5, Şevket Evran6, Enes Akkaya7, Onur Karaca8. 1. Department of Neurosurgery, School of Medicine, Koç University, İstanbul, Turkey. 2. Department of Neurosurgery, İstininye University Liv Hospital, İstanbul, Turkey. Electronic address: dr.serdarcevik@gmail.com. 3. Department of Radiology, Ağrı State Hospital, Ağrı, Turkey. 4. Department of Neurosurgery, Doç. Dr. Yaşar Eryılmaz State Hospital, Ağrı, Turkey. 5. Department of Neurosurgery, Selahaddin Eyyübi State Hospital, Diyarbakır, Turkey. 6. Department of Neurosurgery, Bahçelievler State Hospital, İstanbul, Turkey. 7. Department of Neurosurgery, Arnavutköy State Hospital, İstanbul, Turkey. 8. Department of Department of Anesthesiology and Intensive Care, Aksaray Education and Research Hospital, Aksaray University, Aksaray, Turkey.
Abstract
OBJECTIVE: The present study examined the physical extent of Modic type 1 (MT1) changes and other phenotypic magnetic resonance imaging (MRI) findings in the vertebrae of patients with low back pain (LBP) and MT1 changes. We also identified any correlations of these findings with the severity of pain and the Oswestry Disability Index (ODI). The relationship between the presence of pain and MT1 changes has been examined in several studies. However, to the best of our knowledge, no study has assessed the relationships between pain severity and ODI and the total vertebral area of MT1 involvement. METHODS: After excluding any patient with MT2 or MT3 changes, 49 patients with a diagnosis of LBP and MT1 changes demonstrated on MRI were included. MT1 involvement area, disc height, number of Schmorl's nodes, disc degeneration (Pfirrmann grade), and cross-sectional area of the lumbar muscles were obtained via MRI. Additionally, patient demographic data, body mass index, physical activity level, and disability (ODI) scores were assessed. RESULTS: The total vertebral area of MT1 involvement correlated significantly and positively with the ODI (P = 0.001). In the multivariate linear regression model, with ODI as the dependent variable and age, mean Pfirrmann grade, total vertebral area of MT1 involvement, and sex as independent variables, only the total vertebral area of MT1 involvement was significantly associated with the ODI. CONCLUSIONS: A significant positive correlation was noted between the vertebral MT1 involvement extent and changes in the ODI. Other MRI features of patients with LBP were not related to pain severity or ODI.
OBJECTIVE: The present study examined the physical extent of Modic type 1 (MT1) changes and other phenotypic magnetic resonance imaging (MRI) findings in the vertebrae of patients with low back pain (LBP) and MT1 changes. We also identified any correlations of these findings with the severity of pain and the Oswestry Disability Index (ODI). The relationship between the presence of pain and MT1 changes has been examined in several studies. However, to the best of our knowledge, no study has assessed the relationships between pain severity and ODI and the total vertebral area of MT1 involvement. METHODS: After excluding any patient with MT2 or MT3 changes, 49 patients with a diagnosis of LBP and MT1 changes demonstrated on MRI were included. MT1 involvement area, disc height, number of Schmorl's nodes, disc degeneration (Pfirrmann grade), and cross-sectional area of the lumbar muscles were obtained via MRI. Additionally, patient demographic data, body mass index, physical activity level, and disability (ODI) scores were assessed. RESULTS: The total vertebral area of MT1 involvement correlated significantly and positively with the ODI (P = 0.001). In the multivariate linear regression model, with ODI as the dependent variable and age, mean Pfirrmann grade, total vertebral area of MT1 involvement, and sex as independent variables, only the total vertebral area of MT1 involvement was significantly associated with the ODI. CONCLUSIONS: A significant positive correlation was noted between the vertebral MT1 involvement extent and changes in the ODI. Other MRI features of patients with LBP were not related to pain severity or ODI.
Authors: Lars Christian Haugli Bråten; Elina Iordanova Schistad; Ansgar Espeland; Per Martin Kristoffersen; Anne Julsrud Haugen; Gunn Hege Marchand; Nils Vetti; Are Hugo Pripp; Thomas Istvan Kadar; Jan Sture Skouen; Margreth Grotle; Lars Grøvle; John-Anker Zwart; Jens Ivar Brox; Kjersti Storheim Journal: BMC Musculoskelet Disord Date: 2020-06-10 Impact factor: 2.362
Authors: Per Martin Kristoffersen; Lars C H Bråten; Nils Vetti; Lars Grøvle; Christian Hellum; Kjersti Storheim; John-Anker Zwart; Jörg Assmus; Ansgar Espeland Journal: Eur Radiol Date: 2020-11-27 Impact factor: 5.315
Authors: Per Martin Kristoffersen; Nils Vetti; Kjersti Storheim; Lars Christian Bråten; Mads Peder Rolfsen; Jörg Assmus; Ansgar Espeland Journal: Acta Radiol Open Date: 2020-01-29
Authors: Elisabeth Gjefsen; Lars Christian Haugli Bråten; Guro Løvik Goll; Monica Wigemyr; Nils Bolstad; Morten Valberg; Elina Iordanova Schistad; Gunn Hege Marchand; Fredrik Granviken; Kaja Kristine Selmer; Anne Froholdt; Anne Julsrud Haugen; Magnhild Hammersland Dagestad; Nils Vetti; Gunnstein Bakland; Benedicte Alexandra Lie; Espen A Haavardsholm; Aksel Thuv Nilsen; Thor Einar Holmgard; Thomas Istvan Kadar; Tore Kvien; Jan Sture Skouen; Lars Grøvle; Jens Ivar Brox; Ansgar Espeland; Kjersti Storheim; John Anker Zwart Journal: BMC Musculoskelet Disord Date: 2020-10-21 Impact factor: 2.362