Kristina Arion1, Tuba Aksoy1, Catherine Allaire1, Heather Noga2, Christina Williams1, Mohamed A Bedaiwy1, Paul J Yong3. 1. Department of Obstetrics and Gynecology, University of British Columbia (Drs. Arion, Aksoy, Allaire, Williams, Bedaiwy, and Yong), Vancouver, British Columbia, Canada; BC Women's Centre for Pelvic Pain and Endometriosis (Drs. Arion, Aksoy, Allaire, Noga, Williams, Bedaiwy, and Yong), Vancouver, British Columbia, Canada. 2. BC Women's Centre for Pelvic Pain and Endometriosis (Drs. Arion, Aksoy, Allaire, Noga, Williams, Bedaiwy, and Yong), Vancouver, British Columbia, Canada; Women's Health Research Institute (Drs. Noga and Yong), Vancouver, British Columbia, Canada. 3. Department of Obstetrics and Gynecology, University of British Columbia (Drs. Arion, Aksoy, Allaire, Williams, Bedaiwy, and Yong), Vancouver, British Columbia, Canada; BC Women's Centre for Pelvic Pain and Endometriosis (Drs. Arion, Aksoy, Allaire, Noga, Williams, Bedaiwy, and Yong), Vancouver, British Columbia, Canada; Women's Health Research Institute (Drs. Noga and Yong), Vancouver, British Columbia, Canada.. Electronic address: paul.yong@vch.ca.
Abstract
STUDY OBJECTIVE: To evaluate the point-of-care preoperative transvaginal ultrasound (TVUS) sliding sign in comparison with palpation of a nodule on digital pelvic examination for the prediction of pouch of Douglas (POD) obliteration. DESIGN: Analysis of data from a prospective data registry (Canadian Task Force classification II-2). SETTING: A tertiary referral center. PATIENTS: Women with suspected endometriosis who had preoperative pelvic examination and point-of-care TVUS followed by laparoscopic surgery between August 2015 and December 2016. INTERVENTIONS: Women were preoperatively assessed for the prediction of POD obliteration with pelvic examination for a nodule and point-of-care TVUS uterine/cervix sliding sign. MEASUREMENTS AND MAIN RESULTS: The study included 269 women, 15.2% (41/269) of whom had POD obliteration at the time of surgery. A preoperative negative sliding sign had a sensitivity of 73.2% (95% confidence interval, 57.1%-85.8%) and a specificity of 93.9% (95% CI, 89.9%-96.6%) in the prediction of POD obliteration compared with preoperative palpation of a nodule on pelvic examination, which had a sensitivity of 24.4% (95% CI, 12.4%-40.3%) and a specificity of 93.4% (95% CI, 89.4%-96.3%). The difference in sensitivity was statistically significant (McNemar test, p <.001). A negative sliding sign was also associated with longer operating times and more difficult surgery including the need for ureterolysis. CONCLUSION: The point-of-care TVUS sliding sign showed significantly improved sensitivity compared with palpation of a nodule on pelvic examination for the prediction of POD obliteration. Therefore, the point-of-care TVUS sliding sign improves the preoperative assessment of POD disease and thus may lead to more optimal surgical planning in women with suspected endometriosis.
STUDY OBJECTIVE: To evaluate the point-of-care preoperative transvaginal ultrasound (TVUS) sliding sign in comparison with palpation of a nodule on digital pelvic examination for the prediction of pouch of Douglas (POD) obliteration. DESIGN: Analysis of data from a prospective data registry (Canadian Task Force classification II-2). SETTING: A tertiary referral center. PATIENTS: Women with suspected endometriosis who had preoperative pelvic examination and point-of-care TVUS followed by laparoscopic surgery between August 2015 and December 2016. INTERVENTIONS:Women were preoperatively assessed for the prediction of POD obliteration with pelvic examination for a nodule and point-of-care TVUS uterine/cervix sliding sign. MEASUREMENTS AND MAIN RESULTS: The study included 269 women, 15.2% (41/269) of whom had POD obliteration at the time of surgery. A preoperative negative sliding sign had a sensitivity of 73.2% (95% confidence interval, 57.1%-85.8%) and a specificity of 93.9% (95% CI, 89.9%-96.6%) in the prediction of POD obliteration compared with preoperative palpation of a nodule on pelvic examination, which had a sensitivity of 24.4% (95% CI, 12.4%-40.3%) and a specificity of 93.4% (95% CI, 89.4%-96.3%). The difference in sensitivity was statistically significant (McNemar test, p <.001). A negative sliding sign was also associated with longer operating times and more difficult surgery including the need for ureterolysis. CONCLUSION: The point-of-care TVUS sliding sign showed significantly improved sensitivity compared with palpation of a nodule on pelvic examination for the prediction of POD obliteration. Therefore, the point-of-care TVUS sliding sign improves the preoperative assessment of POD disease and thus may lead to more optimal surgical planning in women with suspected endometriosis.