Literature DB >> 30264005

Rare isolated synchronous splenic metastasis in a patient with type II papillary renal cell carcinoma.

Zhenbang Liu1,2, Marcus Way Lunn Chow1, Alex Hui Chung Lua1, Ronny Ban Wei Tan1.   

Abstract

Metastatic disease is common in renal cell carcinoma (RCC), with a third of cases being synchronous. RCC is known to metastasize to any organ in the body; however, isolated splenic metastasis is extremely rare. We report a case of synchronous splenic metastasis from type II papillary RCC with 80% sarcomatoid change. He was successfully treated with a right radical nephrectomy with en-bloc right liver resection and splenectomy with negative margins to achieve removal of the primary tumour and complete metastasectomy. He underwent 6 cycles adjuvant chemotherapy with Gemcitabine. The patient developed disease recurrence in the spine at the 6th post-operative month with a pathological fracture at T3 and cord indentation for which he underwent posterior decompression and instrumentation and palliative radiotherapy. He recovered well and remains ambulant. Surveillance scans 16 months post-surgery revealed no tumour recurrence or new metastasis.

Entities:  

Keywords:  Metastatic renal cell carcinoma (RCC); metastasectomy; synchronous splenic metastasis

Year:  2018        PMID: 30264005      PMCID: PMC6155692          DOI: 10.21037/acr.2018.02.01

Source DB:  PubMed          Journal:  AME Case Rep        ISSN: 2523-1995


  8 in total

1.  Isolated splenic metastasis in a patient with two distinct genitourinary malignancies.

Authors:  Lulu Zhang; Donald Pasquale; Maithao Le; Raina Patel; Syed Mehdi
Journal:  J Community Support Oncol       Date:  2015-06

2.  Outcomes Following Complete Surgical Metastasectomy for Patients with Metastatic Renal Cell Carcinoma: A Systematic Review and Meta-Analysis.

Authors:  Harras B Zaid; William P Parker; Nida S Safdar; Boris Gershman; Patricia J Erwin; M Hassan Murad; Stephen A Boorjian; Brian A Costello; R Houston Thompson; Bradley C Leibovich
Journal:  J Urol       Date:  2016-07-26       Impact factor: 7.450

3.  The International Metastatic Renal Cell Carcinoma Database Consortium model as a prognostic tool in patients with metastatic renal cell carcinoma previously treated with first-line targeted therapy: a population-based study.

Authors:  Jenny J Ko; Wanling Xie; Nils Kroeger; Jae-Lyun Lee; Brian I Rini; Jennifer J Knox; Georg A Bjarnason; Sandy Srinivas; Sumanta K Pal; Takeshi Yuasa; Martin Smoragiewicz; Frede Donskov; Ravindran Kanesvaran; Lori Wood; D Scott Ernst; Neeraj Agarwal; Ulka N Vaishampayan; Sun-Young Rha; Toni K Choueiri; Daniel Y C Heng
Journal:  Lancet Oncol       Date:  2015-02-12       Impact factor: 41.316

Review 4.  The epidemiology of renal cell carcinoma.

Authors:  Börje Ljungberg; Steven C Campbell; Han Yong Choi; Han Yong Cho; Didier Jacqmin; Jung Eun Lee; Steffen Weikert; Lambertus A Kiemeney
Journal:  Eur Urol       Date:  2011-07-05       Impact factor: 20.096

Review 5.  Isolated splenic metastasis from colorectal cancer.

Authors:  George S Abi Saad; Maher Hussein; Nagi S El-Saghir; Salah Termos; Ala I Sharara; Ali Shamseddine
Journal:  Int J Clin Oncol       Date:  2011-01-22       Impact factor: 3.402

6.  Three Synchronous Atypical Metastases of Clear Cell Renal Carcinoma to the Maxillary Gingiva, Scalp and the Distal Phalanx of the Fifth Digit: A Case Report.

Authors:  Firat Selvi; William C Faquin; Marc Dror Michaelson; Meredith August
Journal:  J Oral Maxillofac Surg       Date:  2016-02-13       Impact factor: 1.895

7.  Size and Volumetric Growth Kinetics of Renal Masses in Patients With Renal Cell Carcinoma.

Authors:  Sin Woo Lee; Hyun Hwan Sung; Hwang Gyun Jeon; Byong Chang Jeong; Seong Soo Jeon; Hyun Moo Lee; Han-Yong Choi; Seong Il Seo
Journal:  Urology       Date:  2016-01-11       Impact factor: 2.649

Review 8.  Splenic metastases: clinicopathologic presentation, differential diagnosis, and pathogenesis.

Authors:  Eva Compérat; Armelle Bardier-Dupas; Philippe Camparo; Frédérique Capron; Frédéric Charlotte
Journal:  Arch Pathol Lab Med       Date:  2007-06       Impact factor: 5.534

  8 in total
  1 in total

1.  Isolated Splenic Metastases from Renal Cell Carcinoma 11 Years after Surgery.

Authors:  Davi Dos Santos Romao; Natally Horvat; Marianne Castro Gonçalves; Emerson Shigueaki Abe; Rodrigo Blanco Dumarco; Publio Cesar Cavalcante Viana; Marcel Cerqueira Cesar Machado
Journal:  Case Rep Med       Date:  2019-09-24
  1 in total

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