Literature DB >> 30263824

Intensifying sulforaphane formation in broccoli sprouts by using other cruciferous sprouts additions.

Hao Liang1, Yongqin Wei1, Ruimin Li1, Li Cheng1, Qipeng Yuan1, Fuping Zheng2.   

Abstract

Sulforaphane is a significant chemopreventive compound which is the predominant glucosinolate in broccoli sprouts. However, the existence of the epithiospecifier protein could direct the hydrolysis of glucosinolates toward sulforaphane nitrile formation instead of sulforaphane. Therefore, the study aimed on improving the yielding of sulforaphane in broccoli sprouts with a new method of the united hydrolysis of cruciferous sprouts. According to the results, the addition of radish, rocket and rape sprouts to broccoli sprouts could promote the hydrolysis of the glucoraphanin to anticancer effective sulforaphane to 2.03, 2.32 and 1.95-fold, respectively, compared to single broccoli sprouts. Meanwhile, the formation of non-bioactive sulforaphane nitrile in these three groups decreased greatly. However, the addition of mustard sprouts had no positive effect. These observations could make a contribution to the potential chemoprotective effects of broccoli sprouts.

Entities:  

Keywords:  Addition; Broccoli sprouts; Glucoraphanin; Hydrolysis; Sulforaphane

Year:  2018        PMID: 30263824      PMCID: PMC6085252          DOI: 10.1007/s10068-018-0347-8

Source DB:  PubMed          Journal:  Food Sci Biotechnol        ISSN: 1226-7708            Impact factor:   2.391


  14 in total

1.  Impact of thermal processing on sulforaphane yield from broccoli ( Brassica oleracea L. ssp. italica).

Authors:  Grace C Wang; Mark Farnham; Elizabeth H Jeffery
Journal:  J Agric Food Chem       Date:  2012-05-15       Impact factor: 5.279

2.  Modifying the processing and handling of frozen broccoli for increased sulforaphane formation.

Authors:  Edward B Dosz; Elizabeth H Jeffery
Journal:  J Food Sci       Date:  2013-08-05       Impact factor: 3.167

3.  Bioavailability and inter-conversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design.

Authors:  John D Clarke; Anna Hsu; Ken Riedl; Deborah Bella; Steven J Schwartz; Jan F Stevens; Emily Ho
Journal:  Pharmacol Res       Date:  2011-07-26       Impact factor: 7.658

4.  Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, sulforaphane and sulforaphane nitrile.

Authors:  N V Matusheski; E H Jeffery
Journal:  J Agric Food Chem       Date:  2001-12       Impact factor: 5.279

5.  Glucosinolates from pak choi and broccoli induce enzymes and inhibit inflammation and colon cancer differently.

Authors:  Doris Lippmann; Carsten Lehmann; Simone Florian; Gitte Barknowitz; Michael Haack; Inga Mewis; Melanie Wiesner; Monika Schreiner; Hansruedi Glatt; Regina Brigelius-Flohé; Anna P Kipp
Journal:  Food Funct       Date:  2014-04-09       Impact factor: 5.396

6.  Breast cancer risk in premenopausal women is inversely associated with consumption of broccoli, a source of isothiocyanates, but is not modified by GST genotype.

Authors:  Christine B Ambrosone; Susan E McCann; Jo L Freudenheim; James R Marshall; Yueshang Zhang; Peter G Shields
Journal:  J Nutr       Date:  2004-05       Impact factor: 4.798

7.  Instability and Structural Change of 4-Methylsulfinyl-3-butenyl Isothiocyanate in the Hydrolytic Process.

Authors:  Dan Song; Hao Liang; Pengqun Kuang; Pingwah Tang; Gaofei Hu; Qipeng Yuan
Journal:  J Agric Food Chem       Date:  2013-05-20       Impact factor: 5.279

Review 8.  Discovery and development of sulforaphane as a cancer chemopreventive phytochemical.

Authors:  Yuesheng Zhang; Li Tang
Journal:  Acta Pharmacol Sin       Date:  2007-09       Impact factor: 6.150

Review 9.  Potential efficacy of broccoli sprouts as a unique supplement for management of type 2 diabetes and its complications.

Authors:  Zahra Bahadoran; Parvin Mirmiran; Fereidoun Azizi
Journal:  J Med Food       Date:  2013-04-30       Impact factor: 2.786

10.  Isothiocyanates, Nitriles, and Epithionitriles from Glucosinolates Are Affected by Genotype and Developmental Stage in Brassica oleracea Varieties.

Authors:  Franziska S Hanschen; Monika Schreiner
Journal:  Front Plant Sci       Date:  2017-06-22       Impact factor: 5.753

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  1 in total

Review 1.  The Burden of Cancer, Government Strategic Policies, and Challenges in Pakistan: A Comprehensive Review.

Authors:  Anwar Ali; Muhammad Faisal Manzoor; Nazir Ahmad; Rana Muhammad Aadil; Hong Qin; Rabia Siddique; Sakhawat Riaz; Arslan Ahmad; Sameh A Korma; Waseem Khalid; Liu Aizhong
Journal:  Front Nutr       Date:  2022-07-22
  1 in total

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