Literature DB >> 3026239

Purification and properties of DNA gyrase from a fluoroquinolone-resistant strain of Escherichia coli.

K Sato, Y Inoue, T Fujii, H Aoyama, M Inoue, S Mitsuhashi.   

Abstract

Subunit A and B proteins of DNA gyrase were separately purified from fluoroquinolone-resistant Escherichia coli GN14181 (MIC of ofloxacin, 100 micrograms/ml) and susceptible strain KL-16. The supercoiling activities of reconstituted Ar+Br (r, resistant) and Ar+Bs (s, susceptible) were 250-fold more resistant to new fluoroquinolones than those of As+Bs and As+Br.

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Year:  1986        PMID： 3026239      PMCID： PMC176532          DOI： 10.1128/AAC.30.5.777

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  20 in total

1.  Structure and activities of Escherichia coli DNA gyrase.

Authors:  C L Peebles; N P Higgins; K N Kreuzer; A Morrison; P O Brown; A Sugino; N R Cozzarelli
Journal:  Cold Spring Harb Symp Quant Biol       Date:  1979

2.  DNA gyrase on the bacterial chromosome: DNA cleavage induced by oxolinic acid.

Authors:  M Snyder; K Drlica
Journal:  J Mol Biol       Date:  1979-06-25       Impact factor: 5.469

3.  DNA gyrase: purification and catalytic properties of a fragment of gyrase B protein.

Authors:  M Gellert; L M Fisher; M H O'Dea
Journal:  Proc Natl Acad Sci U S A       Date:  1979-12       Impact factor: 11.205

Review 4.  Recalibrated linkage map of Escherichia coli K-12.

Authors:  B J Bachmann; K B Low; A L Taylor
Journal:  Bacteriol Rev       Date:  1976-03

5.  Studies on the mechanism of action of nalidixic acid.

Authors:  G J Bourguignon; M Levitt; R Sternglanz
Journal:  Antimicrob Agents Chemother       Date:  1973-10       Impact factor: 5.191

6.  Mode of incomplete cross-resistance among pipemidic, piromidic, and nalidixic acids.

Authors:  S Inoue; T Ohue; J Yamagishi; S Nakamura; M Shimizu
Journal:  Antimicrob Agents Chemother       Date:  1978-08       Impact factor: 5.191

7.  Purification of subunits of Escherichia coli DNA gyrase and reconstitution of enzymatic activity.

Authors:  N P Higgins; C L Peebles; A Sugino; N R Cozzarelli
Journal:  Proc Natl Acad Sci U S A       Date:  1978-04       Impact factor: 11.205

8.  DNA gyrase: subunit structure and ATPase activity of the purified enzyme.

Authors:  K Mizuuchi; M H O'Dea; M Gellert
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

9.  Nalidixic acid resistance: a second genetic character involved in DNA gyrase activity.

Authors:  M Gellert; K Mizuuchi; M H O'Dea; T Itoh; J I Tomizawa
Journal:  Proc Natl Acad Sci U S A       Date:  1977-11       Impact factor: 11.205

10.  In vitro antibacterial activity of AM-715, a new nalidixic acid analog.

Authors:  A Ito; K Hirai; M Inoue; H Koga; S Suzue; T Irikura; S Mitsuhashi
Journal:  Antimicrob Agents Chemother       Date:  1980-02       Impact factor: 5.191
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  49 in total

1.  First clinical isolate of highly fluoroquinolone-resistant Escherichia coli in Scandanavia.

Authors:  M Jonsson; M Walder; A Forsgren
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1990-11       Impact factor: 3.267

2.  Antagonism of wild-type and resistant Escherichia coli and its DNA gyrase by the tricyclic 4-quinolone analogs ofloxacin and S-25930 stereoisomers.

Authors:  J S Wolfson; D C Hooper; E Y Ng; K S Souza; G L McHugh; M N Swartz
Journal:  Antimicrob Agents Chemother       Date:  1987-11       Impact factor: 5.191

3.  Norfloxacin resistance in a clinical isolate of Escherichia coli.

Authors:  H Aoyama; K Sato; T Kato; K Hirai; S Mitsuhashi
Journal:  Antimicrob Agents Chemother       Date:  1987-10       Impact factor: 5.191

4.  Cloning and expression of the norA gene for fluoroquinolone resistance in Staphylococcus aureus.

Authors:  K Ubukata; N Itoh-Yamashita; M Konno
Journal:  Antimicrob Agents Chemother       Date:  1989-09       Impact factor: 5.191

5.  Anucleate cell blue assay: a useful tool for identifying novel type II topoisomerase inhibitors.

Authors:  Yoshihiro Oyamada; Hideaki Ito; Mika Fujimoto-Nakamura; Akihiko Tanitame; Noritaka Iwai; Kazuo Nagai; Jun-Ichi Yamagishi; Masaaki Wachi
Journal:  Antimicrob Agents Chemother       Date:  2006-01       Impact factor: 5.191

6.  Spontaneous quinolone resistance in Serratia marcescens due to a mutation in gyrA.

Authors:  B L Masecar; N J Robillard
Journal:  Antimicrob Agents Chemother       Date:  1991-05       Impact factor: 5.191

7.  In vitro activity of AT-4140 against clinical bacterial isolates.

Authors:  T Kojima; M Inoue; S Mitsuhashi
Journal:  Antimicrob Agents Chemother       Date:  1989-11       Impact factor: 5.191

8.  Contribution of permeability and sensitivity to inhibition of DNA synthesis in determining susceptibilities of Escherichia coli, Pseudomonas aeruginosa, and Alcaligenes faecalis to ciprofloxacin.

Authors:  J Bedard; S Chamberland; S Wong; T Schollaardt; L E Bryan
Journal:  Antimicrob Agents Chemother       Date:  1989-09       Impact factor: 5.191

9.  Emergence of fluoroquinolone-resistant Escherichia coli at a cancer center.

Authors:  W V Kern; E Andriof; M Oethinger; P Kern; J Hacker; R Marre
Journal:  Antimicrob Agents Chemother       Date:  1994-04       Impact factor: 5.191

Review 10.  Mechanisms of resistance to quinolones.

Authors:  E Cambau; L Gutmann
Journal:  Drugs       Date:  1993       Impact factor: 9.546
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