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Literature DB >> 3026176

Genetic studies of low abundance human plasma proteins. III. Polymorphism of the C1R subcomponent of the first complement component.

Abstract

Genetic polymorphism of the C1R subcomponent of human complement component C1 has been detected in normal plasma samples using the high resolving power of isoelectric focusing in 6 M urea followed by immunoblotting. There are two common alleles at the C1R structural locus that show autosomal codominant inheritance. The C1R*1 and C1R*2 allele frequencies in U.S. white and U.S. black blood donors are: .934, .066, and .899, .101, respectively.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1986 PMID： 3026176 PMCID： PMC1684130

Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025

18 in total

1. Active disassembly of the first complement component, C-1, by C-1 inactivator.

Authors: R J Ziccardi; N R Cooper
Journal: J Immunol Date: 1979-08 Impact factor: 5.422

2. Chemistry and biologic activity of the complement system.

Authors: S Ruddy
Journal: Transplant Proc Date: 1974-03 Impact factor: 1.066

Review 3. Genetics of the complement system.

Authors: C A Alper; F S Rosen
Journal: Adv Hum Genet Date: 1976

4. Inherited structural variation and linkage relationships of C7.

Authors: M J Hobart; V Joysey; P J Lachmann
Journal: J Immunogenet Date: 1978-06

5. The subunit composition and sedimentation properties of human C1.

Authors: R J Ziccardi; N R Cooper
Journal: J Immunol Date: 1977-06 Impact factor: 5.422

6. Assembly of subcomponents C1r and C1s of first component of complement: electron microscopic and ultracentrifugal studies.

Authors: J Tschopp; W Villiger; H Fuchs; E Kilchherr; J Engel
Journal: Proc Natl Acad Sci U S A Date: 1980-12 Impact factor: 11.205

7. The structure and enzymic activities of the C1r and C1s subcomponents of C1, the first component of human serum complement.

Authors: R B Sim; R R Porter; K B Reid; I Gigli
Journal: Biochem J Date: 1977-05-01 Impact factor: 3.857

1. Genetic studies of low-abundance human plasma proteins. IX. A new allele at the complement subcomponent C1R structural locus.

Authors: M I Kamboh; L Lyons; R E Ferrell
Journal: Hum Genet Date: 1988-12 Impact factor: 4.132

1 in total