Literature DB >> 30257890

Venous Thromboembolism in Patients with Sarcoma: A Retrospective Study.

Thierry Alcindor1,2, Ali Al-Fakeeh3,4, Krista Goulding3,5, Susan Solymoss3,2, Nathalie Ste-Marie5, Robert Turcotte3,5.   

Abstract

BACKGROUND: Little has been published about the association of venous thromboembolism (VTE) and sarcoma. In this study, we sought to identify clinical features of patients with sarcoma presenting at least one VTE episode.
METHODS: Our study was a retrospective case-control study of a single-institution database with univariate and multivariate analysis using chi-square and Student's t test. A p value less than .05 was considered significant.
RESULTS: The overall incidence of VTE in patients with sarcoma was 7.9%. Predictive factors identified by multivariate analysis were metastatic disease and administration of chemotherapy. It was not statistically possible to correlate the risk of VTE with specific sarcoma subtypes, but observations suggested malignant peripheral nerve sheath tumor, osteosarcoma, and liposarcoma as having the highest propension.
CONCLUSION: VTE is not infrequent in patients with sarcoma. Adoption of common guidelines for cancer-associated thrombosis is recommended. © AlphaMed Press 2018.

Entities:  

Mesh：

Year:  2018        PMID： 30257890      PMCID： PMC6519765          DOI： 10.1634/theoncologist.2018-0081

Source DB:  PubMed          Journal:  Oncologist        ISSN： 1083-7159


  13 in total

1.  Epidemiology of first and recurrent venous thromboembolism in patients with active cancer. A population-based cohort study.

Authors:  Alexander T Cohen; Anja Katholing; Stephan Rietbrock; Luke Bamber; Carlos Martinez
Journal:  Thromb Haemost       Date:  2016-10-06       Impact factor: 5.249

2.  Gemcitabine versus gemcitabine plus dalteparin thromboprophylaxis in pancreatic cancer.

Authors:  A Maraveyas; J Waters; R Roy; D Fyfe; D Propper; F Lofts; J Sgouros; E Gardiner; K Wedgwood; C Ettelaie; G Bozas
Journal:  Eur J Cancer       Date:  2011-11-17       Impact factor: 9.162

3.  Epidemiology of venous thromboembolism in hematological cancers: The Scandinavian Thrombosis and Cancer (STAC) cohort.

Authors:  Inger Lise Gade; Sigrid Brækkan; Inger Anne Næss; John-Bjarne Hansen; Frits Rosendaal; Suzanne Cannegieter; Kim Overvad; Hilde Jensvoll; Jens Hammerstrøm; Olga Vikhammer Gran; Anne Tjønneland; Søren Risom Kristensen; Marianne Tang Severinsen
Journal:  Thromb Res       Date:  2017-09-05       Impact factor: 3.944

4.  Risk of venous thromboembolism in bone and soft-tissue sarcoma patients undergoing surgical intervention: a report from prior to the initiation of SCIP measures.

Authors:  Timothy A Damron; Zabi Wardak; Bradley Glodny; William Grant
Journal:  J Surg Oncol       Date:  2011-03-02       Impact factor: 3.454

Review 5.  Tumor-derived tissue factor-positive microparticles and venous thrombosis in cancer patients.

Authors:  Julia E Geddings; Nigel Mackman
Journal:  Blood       Date:  2013-06-24       Impact factor: 22.113

Review 6.  Refinements in Sarcoma Classification in the Current 2013 World Health Organization Classification of Tumours of Soft Tissue and Bone.

Authors:  Vickie Y Jo; Leona A Doyle
Journal:  Surg Oncol Clin N Am       Date:  2016-07-30       Impact factor: 3.495

7.  The impact of initial cancer stage on the incidence of venous thromboembolism: the Scandinavian Thrombosis and Cancer (STAC) Cohort.

Authors:  I L Gade; S K Braekkan; I A Naess; J-B Hansen; S C Cannegieter; K Overvad; H Jensvoll; J Hammerstrøm; K Blix; A Tjønneland; S R Kristensen; M T Severinsen
Journal:  J Thromb Haemost       Date:  2017-07-11       Impact factor: 5.824

8.  Semuloparin for thromboprophylaxis in patients receiving chemotherapy for cancer.

Authors:  Giancarlo Agnelli; Daniel J George; Ajay K Kakkar; William Fisher; Michael R Lassen; Patrick Mismetti; Patrick Mouret; Umesh Chaudhari; Francesca Lawson; Alexander G G Turpie
Journal:  N Engl J Med       Date:  2012-02-16       Impact factor: 91.245

Review 9.  Cancer and Venous Thromboembolic Disease: A Review.

Authors:  Eoin Donnellan; Alok A Khorana
Journal:  Oncologist       Date:  2017-02-07

10.  Venous thromboembolism prophylaxis and treatment in patients with cancer: american society of clinical oncology clinical practice guideline update 2014.

Authors:  Gary H Lyman; Kari Bohlke; Alok A Khorana; Nicole M Kuderer; Agnes Y Lee; Juan Ignacio Arcelus; Edward P Balaban; Jeffrey M Clarke; Christopher R Flowers; Charles W Francis; Leigh E Gates; Ajay K Kakkar; Nigel S Key; Mark N Levine; Howard A Liebman; Margaret A Tempero; Sandra L Wong; Mark R Somerfield; Anna Falanga
Journal:  J Clin Oncol       Date:  2015-01-20       Impact factor: 44.544
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  1 in total

1.  Intraoperative considerations in a patient with chondroblastic osteosarcoma and saddle pulmonary embolism undergoing amputation.

Authors:  William B Smisson; Henrique Vale; Arvind Chandrashekar; Bryan J Hierlmeier
Journal:  Clin Case Rep       Date:  2020-03-20
  1 in total

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