Literature DB >> 30255568

Clinical proof of concept for a safe and effective NF-κB-targeting strategy in multiple myeloma.

Laura Tornatore1, Daria Capece1, Daniel D'Andrea1, Federica Begalli1, Daniela Verzella1, Jason Bennett1, Gary Acton2, Elizabeth A Campbell3, James Kelly4, Michael Tarbit5, Nigel Adams6, Selina Bannoo1, Antonio Leonardi7, Annamaria Sandomenico8, Domenico Raimondo9, Menotti Ruvo8, Angela Chambery10, Metod Oblak11, Magda J Al-Obaidi12, Richard S Kaczmarski13, Ian Gabriel12, Heather E Oakervee14, Martin F Kaiser15, Ashutosh Wechalekar16, Reuben Benjamin17, Jane F Apperley18, Holger W Auner18,19, Guido Franzoso1.   

Abstract

Entities:  

Keywords:  NF-κB; apoptosis; clinical trials; drug; multiple myeloma

Mesh：

Substances：

Year:  2018        PMID： 30255568     DOI： 10.1111/bjh.15569

Source DB:  PubMed          Journal:  Br J Haematol        ISSN： 0007-1048            Impact factor:   6.998


× No keyword cloud information.
  10 in total

1.  Gadd45 in Normal Hematopoiesis and Leukemia.

Authors:  Dan A Liebermann
Journal:  Adv Exp Med Biol       Date:  2022       Impact factor: 2.622

Review 2.  Roles for GADD45 in Development and Cancer.

Authors:  Kishan Patel; Mary Grace Murray; Kelly A Whelan
Journal:  Adv Exp Med Biol       Date:  2022       Impact factor: 2.622

3.  RING finger 138 deregulation distorts NF-кB signaling and facilities colitis switch to aggressive malignancy.

Authors:  Yalan Lu; Rong Huang; Jianming Ying; Xingchen Li; Tao Jiao; Lei Guo; Haitao Zhou; Han Wang; Amannisa Tuersuntuoheti; Jianmei Liu; Qichen Chen; Yanhong Wang; Luying Su; Changyuan Guo; Fu Xu; Ziyi Wang; Yan Lu; Kai Li; Junbo Liang; Zhen Huang; Xiao Chen; Jinjie Yao; Hanjie Hu; Xiaowen Cheng; Yufeng Wan; Xinyan Chen; Ning Zhang; Shiying Miao; Jianqiang Cai; Linfang Wang; Changzheng Liu; Wei Song; Hong Zhao
Journal:  Signal Transduct Target Ther       Date:  2022-06-13

Review 4.  NFκB and Kidney Injury.

Authors:  Ning Song; Friedrich Thaiss; Linlin Guo
Journal:  Front Immunol       Date:  2019-04-16       Impact factor: 7.561

5.  Preclinical toxicology and safety pharmacology of the first-in-class GADD45β/MKK7 inhibitor and clinical candidate, DTP3.

Authors:  Laura Tornatore; Daria Capece; Daniel D'Andrea; Federica Begalli; Daniela Verzella; Jason Bennett; Gary Acton; Elizabeth A Campbell; James Kelly; Michael Tarbit; Nigel Adams; Selina Bannoo; Antonio Leonardi; Annamaria Sandomenico; Domenico Raimondo; Menotti Ruvo; Angela Chambery; Metod Oblak; Magda J Al-Obaidi; Richard S Kaczmarski; Ian Gabriel; Heather E Oakervee; Martin F Kaiser; Ashutosh Wechalekar; Reuben Benjamin; Jane F Apperley; Holger W Auner; Guido Franzoso
Journal:  Toxicol Rep       Date:  2019-04-19

6.  Insights into the Interaction Mechanism of DTP3 with MKK7 by Using STD-NMR and Computational Approaches.

Authors:  Annamaria Sandomenico; Lorenzo Di Rienzo; Luisa Calvanese; Emanuela Iaccarino; Gabriella D'Auria; Lucia Falcigno; Angela Chambery; Rosita Russo; Guido Franzoso; Laura Tornatore; Marco D'Abramo; Menotti Ruvo; Edoardo Milanetti; Domenico Raimondo
Journal:  Biomedicines       Date:  2020-12-30

7.  Report of the 24th Meeting on Signal Transduction 2021.

Authors:  Bastian Schirmer; Klaudia Giehl; Katharina F Kubatzky
Journal:  Int J Mol Sci       Date:  2022-02-11       Impact factor: 5.923

8.  The Screening of Combinatorial Peptide Libraries for Targeting Key Molecules or Protein-Protein Interactions in the NF-κB Pathway.

Authors:  Laura Tornatore; Daria Capece; Annamaria Sandomenico; Daniela Verzella; Davide Vecchiotti; Francesca Zazzeroni; Menotti Ruvo; Guido Franzoso
Journal:  Methods Mol Biol       Date:  2021

Review 9.  Life, death, and autophagy in cancer: NF-κB turns up everywhere.

Authors:  Daniela Verzella; Alessandra Pescatore; Daria Capece; Davide Vecchiotti; Matilde Valeria Ursini; Guido Franzoso; Edoardo Alesse; Francesca Zazzeroni
Journal:  Cell Death Dis       Date:  2020-03-30       Impact factor: 8.469

10.  Mathematical modelling of the role of GADD45β in the pathogenesis of multiple myeloma.

Authors:  Yao Zhang; Changqing Zhen; Qing Yang; Bing Ji
Journal:  R Soc Open Sci       Date:  2020-05-13       Impact factor: 2.963
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.