| Literature DB >> 30251219 |
Lichan Tao1, Jia Shi2, Xiaoyu Yang1, Ling Yang3, Fei Hua4.
Abstract
Diabetic cardiomyopathy (DCM) or diabetes-induced cardiac dysfunction is a direct consequence of uncontrolled metabolic syndrome and occurs worldwide. However, the underlying cellular and molecular mechanisms remain poorly understood. Recently, exosomes have attracted considerable interest for their use as efficient, targeted, and non-immunogenic delivery systems for biological molecules or pharmacotherapies. This review will summarize the fast-developing field of the regulation and function of exosomes in DCM, affording valuable insights and therapeutic opportunities in combatting diabetes-related cardiac disorder for modern human health.Entities:
Keywords: Diabetic cardiomyopathy; Exosomes
Mesh:
Year: 2018 PMID: 30251219 DOI: 10.1007/s12265-018-9825-x
Source DB: PubMed Journal: J Cardiovasc Transl Res ISSN: 1937-5387 Impact factor: 4.132