Literature DB >> 30251219

The Exosome: a New Player in Diabetic Cardiomyopathy.

Lichan Tao1, Jia Shi2, Xiaoyu Yang1, Ling Yang3, Fei Hua4.   

Abstract

Diabetic cardiomyopathy (DCM) or diabetes-induced cardiac dysfunction is a direct consequence of uncontrolled metabolic syndrome and occurs worldwide. However, the underlying cellular and molecular mechanisms remain poorly understood. Recently, exosomes have attracted considerable interest for their use as efficient, targeted, and non-immunogenic delivery systems for biological molecules or pharmacotherapies. This review will summarize the fast-developing field of the regulation and function of exosomes in DCM, affording valuable insights and therapeutic opportunities in combatting diabetes-related cardiac disorder for modern human health.

Entities:  

Keywords:  Diabetic cardiomyopathy; Exosomes

Mesh:

Year:  2018        PMID: 30251219     DOI: 10.1007/s12265-018-9825-x

Source DB:  PubMed          Journal:  J Cardiovasc Transl Res        ISSN: 1937-5387            Impact factor:   4.132


  45 in total

Review 1.  Microvesicles and exosomes: new players in metabolic and cardiovascular disease.

Authors:  Charlotte Lawson; Jose M Vicencio; Derek M Yellon; Sean M Davidson
Journal:  J Endocrinol       Date:  2016-01-07       Impact factor: 4.286

2.  Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes.

Authors:  Joanna Kowal; Guillaume Arras; Marina Colombo; Mabel Jouve; Jakob Paul Morath; Bjarke Primdal-Bengtson; Florent Dingli; Damarys Loew; Mercedes Tkach; Clotilde Théry
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-08       Impact factor: 11.205

Review 3.  Microvesicles - potential biomarkers for the interrelations atherosclerosis/type 2 diabetes mellitus.

Authors:  Sorina Maria Aurelian; Dan Mircea Cheţa; Doina Onicescu
Journal:  Rom J Morphol Embryol       Date:  2014       Impact factor: 1.033

Review 4.  The potential of endurance exercise-derived exosomes to treat metabolic diseases.

Authors:  Adeel Safdar; Ayesha Saleem; Mark A Tarnopolsky
Journal:  Nat Rev Endocrinol       Date:  2016-05-27       Impact factor: 43.330

Review 5.  The Exosome-Derived Biomarker in Atherosclerosis and Its Clinical Application.

Authors:  Mengmeng Lu; Shuaifang Yuan; Shicheng Li; Ling Li; Min Liu; Shaogui Wan
Journal:  J Cardiovasc Transl Res       Date:  2018-05-25       Impact factor: 4.132

6.  Exosomes secreted from GATA-4 overexpressing mesenchymal stem cells serve as a reservoir of anti-apoptotic microRNAs for cardioprotection.

Authors:  Bin Yu; Ha Won Kim; Min Gong; Jingcai Wang; Ronald W Millard; Yigang Wang; Muhammad Ashraf; Meifeng Xu
Journal:  Int J Cardiol       Date:  2014-12-23       Impact factor: 4.164

7.  The effect of exercise and oxidant-antioxidant intervention on the levels of neurotrophins and free radicals in spinal cord of rats.

Authors:  S Siamilis; J Jakus; C Nyakas; A Costa; B Mihalik; A Falus; Z Radak
Journal:  Spinal Cord       Date:  2008-10-21       Impact factor: 2.772

Review 8.  Endothelial cell-cardiomyocyte crosstalk in diabetic cardiomyopathy.

Authors:  Andrea Wan; Brian Rodrigues
Journal:  Cardiovasc Res       Date:  2016-06-10       Impact factor: 10.787

9.  Cardioprotection mediated by exosomes is impaired in the setting of type II diabetes but can be rescued by the use of non-diabetic exosomes in vitro.

Authors:  Sean M Davidson; Jaime A Riquelme; Kaloyan Takov; Jose M Vicencio; Claire Boi-Doku; Vanessa Khoo; Christian Doreth; Dina Radenkovic; Sergio Lavandero; Derek M Yellon
Journal:  J Cell Mol Med       Date:  2017-08-25       Impact factor: 5.310

Review 10.  Exosomes: Mechanisms of Uptake.

Authors:  Kelly J McKelvey; Katie L Powell; Anthony W Ashton; Jonathan M Morris; Sharon A McCracken
Journal:  J Circ Biomark       Date:  2015-07-17
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  6 in total

1.  Exosomes in Cardiovascular Diseases and Treatment: Experimental and Clinical Aspects.

Authors:  Jing Wang; Chenglin Zhao; Junjie Xiao
Journal:  J Cardiovasc Transl Res       Date:  2019-01-07       Impact factor: 4.132

Review 2.  Heart failure in diabetes.

Authors:  Stanislovas S Jankauskas; Urna Kansakar; Fahimeh Varzideh; Scott Wilson; Pasquale Mone; Angela Lombardi; Jessica Gambardella; Gaetano Santulli
Journal:  Metabolism       Date:  2021-10-08       Impact factor: 8.694

Review 3.  Exploring the key communicator role of exosomes in cancer microenvironment through proteomics.

Authors:  HuiSu Kim; Dong Wook Kim; Je-Yoel Cho
Journal:  Proteome Sci       Date:  2019-10-29       Impact factor: 2.480

Review 4.  The Art of Intercellular Wireless Communications: Exosomes in Heart Disease and Therapy.

Authors:  Mallikarjun Patil; John Henderson; Hien Luong; Divya Annamalai; Gopalkrishna Sreejit; Prasanna Krishnamurthy
Journal:  Front Cell Dev Biol       Date:  2019-12-03

Review 5.  The role of extracellular vesicles in regulating local and systemic inflammation in cardiovascular disease.

Authors:  Lee Ohayon; Xinyi Zhang; Partha Dutta
Journal:  Pharmacol Res       Date:  2021-06-25       Impact factor: 10.334

Review 6.  Extracellular Vesicles in Type 1 Diabetes: A Versatile Tool.

Authors:  Caitlin N Suire; Mangesh D Hade
Journal:  Bioengineering (Basel)       Date:  2022-03-04
  6 in total

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