Literature DB >> 30246208

A synthetic model of the nonheme iron-superoxo intermediate of cysteine dioxygenase.

Anne A Fischer1, Sergey V Lindeman1, Adam T Fiedler1.   

Abstract

A nonheme Fe(ii) complex (1) that models substrate-bound cysteine dioxygenase (CDO) reacts with O2 at -80 °C to yield a purple intermediate (2). Analysis with spectroscopic and computational methods determined that 2 features a thiolate-ligated Fe(iii) center bound to a superoxide radical, mimicking the putative structure of a key CDO intermediate.

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Year:  2018        PMID： 30246208      PMCID： PMC6201693          DOI： 10.1039/c8cc06247a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  30 in total

1.  Dioxygenation of cysteamine to hypotaurine at a tris(pyrazolyl)borate iron(ii) unit - cysteamine dioxygenase mimicking?

Authors:  M Sallmann; B Braun; C Limberg
Journal:  Chem Commun (Camb)       Date:  2015-04-21       Impact factor: 6.222

2.  Spectroscopic and computational characterization of substrate-bound mouse cysteine dioxygenase: nature of the ferrous and ferric cysteine adducts and mechanistic implications.

Authors:  Jessica D Gardner; Brad S Pierce; Brian G Fox; Thomas C Brunold
Journal:  Biochemistry       Date:  2010-07-27       Impact factor: 3.162

Review 3.  Mechanisms of L-cysteine neurotoxicity.

Authors:  R Janáky; V Varga; A Hermann; P Saransaari; S S Oja
Journal:  Neurochem Res       Date:  2000-10       Impact factor: 3.996

4.  Characterization of Mononuclear Non-heme Iron(III)-Superoxo Complex with a Five-Azole Ligand Set.

Authors:  Frédéric Oddon; Yosuke Chiba; Jun Nakazawa; Takehiro Ohta; Takashi Ogura; Shiro Hikichi
Journal:  Angew Chem Int Ed Engl       Date:  2015-05-04       Impact factor: 15.336

5.  Intermediates in the oxygenation of a nonheme diiron(II) complex, including the first evidence for a bound superoxo species.

Authors:  Xiaopeng Shan; Lawrence Que
Journal:  Proc Natl Acad Sci U S A       Date:  2005-03-31       Impact factor: 11.205

Review 6.  Thiol dioxygenases: unique families of cupin proteins.

Authors:  Martha H Stipanuk; Chad R Simmons; P Andrew Karplus; John E Dominy
Journal:  Amino Acids       Date:  2010-03-01       Impact factor: 3.520

7.  An insight into the mechanism of human cysteine dioxygenase. Key roles of the thioether-bonded tyrosine-cysteine cofactor.

Authors:  Sheng Ye; Xiao'ai Wu; Lei Wei; Danming Tang; Ping Sun; Mark Bartlam; Zihe Rao
Journal:  J Biol Chem       Date:  2006-11-29       Impact factor: 5.157

8.  A Structurally Characterized Nonheme Cobalt-Hydroperoxo Complex Derived from Its Superoxo Intermediate via Hydrogen Atom Abstraction.

Authors:  Chun-Chieh Wang; Hao-Ching Chang; Yei-Chen Lai; Huayi Fang; Chieh-Chin Li; Hung-Kai Hsu; Zong-Yan Li; Tien-Sung Lin; Ting-Shen Kuo; Frank Neese; Shengfa Ye; Yun-Wei Chiang; Ming-Li Tsai; Wen-Feng Liaw; Way-Zen Lee
Journal:  J Am Chem Soc       Date:  2016-10-20       Impact factor: 15.419

9.  Sulfate metabolism is abnormal in patients with rheumatoid arthritis. Confirmation by in vivo biochemical findings.

Authors:  H Bradley; A Gough; R S Sokhi; A Hassell; R Waring; P Emery
Journal:  J Rheumatol       Date:  1994-07       Impact factor: 4.666

10.  Spectroscopic Evidence for the Two C-H-Cleaving Intermediates of Aspergillus nidulans Isopenicillin N Synthase.

Authors:  Esta Tamanaha; Bo Zhang; Yisong Guo; Wei-Chen Chang; Eric W Barr; Gang Xing; Jennifer St Clair; Shengfa Ye; Frank Neese; J Martin Bollinger; Carsten Krebs
Journal:  J Am Chem Soc       Date:  2016-07-05       Impact factor: 15.419
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  9 in total

1.  A Nonheme Thiolate-Ligated Cobalt Superoxo Complex: Synthesis and Spectroscopic Characterization, Computational Studies, and Hydrogen Atom Abstraction Reactivity.

Authors:  Jesse B Gordon; Avery C Vilbert; Maxime A Siegler; Kyle M Lancaster; Pierre Moënne-Loccoz; David P Goldberg
Journal:  J Am Chem Soc       Date:  2019-02-18       Impact factor: 15.419

2.  Superoxide Oxidation by a Thiolate-Ligated Iron Complex and Anion Inhibition.

Authors:  Maksym A Dedushko; Jessica H Pikul; Julie A Kovacs
Journal:  Inorg Chem       Date:  2021-04-26       Impact factor: 5.165

3.  An Iron(III) Superoxide Corrole from Iron(II) and Dioxygen.

Authors:  Jireh Joy D Sacramento; Therese Albert; Maxime Siegler; Pierre Moënne-Loccoz; David P Goldberg
Journal:  Angew Chem Int Ed Engl       Date:  2021-11-30       Impact factor: 15.336

4.  Electronic Structure and Reactivity of Dioxygen-Derived Aliphatic Thiolate-Ligated Fe-Peroxo and Fe(IV) Oxo Compounds.

Authors:  Maksym A Dedushko; Maria B Greiner; Alexandra N Downing; Michael Coggins; Julie A Kovacs
Journal:  J Am Chem Soc       Date:  2022-05-06       Impact factor: 16.383

5.  Structures, Spectroscopic Properties, and Dioxygen Reactivity of 5- and 6-Coordinate Nonheme Iron(II) Complexes: A Combined Enzyme/Model Study of Thiol Dioxygenases.

Authors:  Jesse B Gordon; Jeremy P McGale; Joshua R Prendergast; Zahra Shirani-Sarmazeh; Maxime A Siegler; Guy N L Jameson; David P Goldberg
Journal:  J Am Chem Soc       Date:  2018-10-22       Impact factor: 15.419

6.  Formation of a Reactive, Alkyl Thiolate-Ligated FeIII-Superoxo Intermediate Derived from Dioxygen.

Authors:  Maike N Blakely; Maksym A Dedushko; Penny Chaau Yan Poon; Gloria Villar-Acevedo; Julie A Kovacs
Journal:  J Am Chem Soc       Date:  2019-01-24       Impact factor: 15.419

7.  Proton-Coupled Electron-Transfer Reactivity Controls Iron versus Sulfur Oxidation in Nonheme Iron-Thiolate Complexes.

Authors:  Jesse B Gordon; Jeremy P McGale; Maxime A Siegler; David P Goldberg
Journal:  Inorg Chem       Date:  2021-04-19       Impact factor: 5.165

8.  Electronic structures and spectroscopic signatures of diiron intermediates generated by O2 activation of nonheme iron(II)-thiolate complexes.

Authors:  Danushka M Ekanayake; Dao Pham; Andrew L Probst; Joshua R Miller; Codrina V Popescu; Adam T Fiedler
Journal:  Dalton Trans       Date:  2021-10-19       Impact factor: 4.569

9.  Nonheme iron-thiolate complexes as structural models of sulfoxide synthase active sites.

Authors:  Danushka M Ekanayake; Anne A Fischer; Maya E Elwood; Alexandra M Guzek; Sergey V Lindeman; Codrina V Popescu; Adam T Fiedler
Journal:  Dalton Trans       Date:  2020-12-22       Impact factor: 4.390
  9 in total

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