Literature DB >> 25786780

Dioxygenation of cysteamine to hypotaurine at a tris(pyrazolyl)borate iron(ii) unit - cysteamine dioxygenase mimicking?

M Sallmann1, B Braun, C Limberg.   

Abstract

A novel complex Tp(Me,Ph)Fe(SCH2CH2NH2) has been synthesized as a speculative model for ADO. Indeed its reaction with O2 led to the dioxygenation of the S atom and thus to hypotaurine. This finding may allow us to draw conclusions on the constitution of the ADO active site, whose structure is still unknown.

Entities:  

Mesh：

Substances：

Year:  2015        PMID： 25786780     DOI： 10.1039/c5cc01083g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

1.  A Nonheme Thiolate-Ligated Cobalt Superoxo Complex: Synthesis and Spectroscopic Characterization, Computational Studies, and Hydrogen Atom Abstraction Reactivity.

Authors:  Jesse B Gordon; Avery C Vilbert; Maxime A Siegler; Kyle M Lancaster; Pierre Moënne-Loccoz; David P Goldberg
Journal:  J Am Chem Soc       Date:  2019-02-18       Impact factor: 15.419

2.  Synthesis, X-ray Structures, Electronic Properties, and O2/NO Reactivities of Thiol Dioxygenase Active-Site Models.

Authors:  Anne A Fischer; Nuru Stracey; Sergey V Lindeman; Thomas C Brunold; Adam T Fiedler
Journal:  Inorg Chem       Date:  2016-11-01       Impact factor: 5.165

Review 3.  Understanding human thiol dioxygenase enzymes: structure to function, and biology to pathology.

Authors:  Bibekananda Sarkar; Mahesh Kulharia; Anil K Mantha
Journal:  Int J Exp Pathol       Date:  2017-04-24       Impact factor: 1.925

Review 4.  Activation of Dioxygen by Iron and Manganese Complexes: A Heme and Nonheme Perspective.

Authors:  Sumit Sahu; David P Goldberg
Journal:  J Am Chem Soc       Date:  2016-08-30       Impact factor: 15.419

5.  Structures, Spectroscopic Properties, and Dioxygen Reactivity of 5- and 6-Coordinate Nonheme Iron(II) Complexes: A Combined Enzyme/Model Study of Thiol Dioxygenases.

Authors:  Jesse B Gordon; Jeremy P McGale; Joshua R Prendergast; Zahra Shirani-Sarmazeh; Maxime A Siegler; Guy N L Jameson; David P Goldberg
Journal:  J Am Chem Soc       Date:  2018-10-22       Impact factor: 15.419

6.  A synthetic model of the nonheme iron-superoxo intermediate of cysteine dioxygenase.

Authors:  Anne A Fischer; Sergey V Lindeman; Adam T Fiedler
Journal:  Chem Commun (Camb)       Date:  2018-09-24       Impact factor: 6.222

7.  Electronic structures and spectroscopic signatures of diiron intermediates generated by O2 activation of nonheme iron(II)-thiolate complexes.

Authors:  Danushka M Ekanayake; Dao Pham; Andrew L Probst; Joshua R Miller; Codrina V Popescu; Adam T Fiedler
Journal:  Dalton Trans       Date:  2021-10-19       Impact factor: 4.569
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.