Literature DB >> 30243833

Overview of Biochemical Assays in Lipidic Cubic Phase.

Zhu Lan1, Ming-Yue Lee1, Eugene Chun1, Bin Liu1, Wei Liu2.   

Abstract

The development of novel biochemical methods to efficiently characterize membrane protein (MP) properties in lipidic cubic phase (LCP) is important for studying complicated MPs and their multimeric complexes. Here, we summarize recent LCP-related assays and provide an outlook on their applications in structure and function studies of MPs.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Keywords:  LCP; crystallization; functional assay; membrane protein; protein stability

Mesh:

Substances:

Year:  2018        PMID: 30243833     DOI: 10.1016/j.tibs.2018.08.008

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


  2 in total

Review 1.  Serial Crystallography for Structure-Based Drug Discovery.

Authors:  Lan Zhu; Xiaoyu Chen; Enrique E Abola; Liang Jing; Wei Liu
Journal:  Trends Pharmacol Sci       Date:  2020-09-16       Impact factor: 14.819

2.  Structure Determination from Lipidic Cubic Phase Embedded Microcrystals by MicroED.

Authors:  Lan Zhu; Guanhong Bu; Liang Jing; Dan Shi; Ming-Yue Lee; Tamir Gonen; Wei Liu; Brent L Nannenga
Journal:  Structure       Date:  2020-07-30       Impact factor: 5.006

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.