Literature DB >> 3024161

Localization of Epstein-Barr virus-encoded small RNAs by in situ hybridization.

J G Howe, J A Steitz.   

Abstract

Human B lymphocytes latently infected with Epstein-Barr virus (EBV) synthesize two low molecular weight RNAs designated EBER 1 and 2. Using an in situ hybridization technique we have localized EBER 1 and 2 within the nucleus of single EBV-harboring B lymphocytes from established and recently transformed cell lines. As controls, the locations of the small nuclear RNA, U1, and the small cytoplasmic RNA, 7SL, were examined in HeLa and EBV-harboring cells. Because of possible functional similarities between EBERs and the adenovirus-associated (VA) RNAs, VAI was also localized; it appeared to be in the nucleus and cytoplasm, implying that VAI may have a different role than that of the nuclear-localized EBERs.

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Year:  1986        PMID： 3024161      PMCID： PMC387063          DOI： 10.1073/pnas.83.23.9006

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  40 in total

1.  Detection of viral sequences of low reiteration frequency by in situ hybridization.

Authors:  M Brahic; A T Haase
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

2.  Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNA.

Authors:  P A Reichel; W C Merrick; J Siekierka; M B Mathews
Journal:  Nature       Date:  1985 Jan 17-23       Impact factor: 49.962

3.  Constitutive expression of Epstein-Barr virus-encoded RNAs and nuclear antigen during latency and after induction of Epstein-Barr virus replication.

Authors:  R Weigel; D K Fischer; L Heston; G Miller
Journal:  J Virol       Date:  1985-01       Impact factor: 5.103

4.  An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells.

Authors:  D Wang; D Liebowitz; E Kieff
Journal:  Cell       Date:  1985-12       Impact factor: 41.582

5.  Studies on human lymphocytes in vitro. IV. Comparative fine structural features of the established Burkitt lymphoma cell lines AL-1, EB-2 and phytomitogen-transformed lymphocytes.

Authors:  S D Douglas; J Borjeson; L N Chessin
Journal:  J Immunol       Date:  1967-08       Impact factor: 5.422

6.  A mechanism for the control of protein synthesis by adenovirus VA RNAI.

Authors:  R P O'Malley; T M Mariano; J Siekierka; M B Mathews
Journal:  Cell       Date:  1986-02-14       Impact factor: 41.582

7.  Characterization of the major Epstein-Barr virus-specific RNA in Burkitt lymphoma-derived cells.

Authors:  J R Arrand; L Rymo
Journal:  J Virol       Date:  1982-02       Impact factor: 5.103

8.  Determination of nucleotide sequences from double-stranded regions of HeLa cell nuclear RNA.

Authors:  H D Robertson; E Dickson; W Jelinek
Journal:  J Mol Biol       Date:  1977-10-05       Impact factor: 5.469

9.  Role of DNA-dependent RNA polymerases II and III in transcription of the adenovirus genome late in productive infection.

Authors:  R Weinmann; H J Raskas; R G Roeder
Journal:  Proc Natl Acad Sci U S A       Date:  1974-09       Impact factor: 11.205

10.  Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells.

Authors:  J P Hendrick; S L Wolin; J Rinke; M R Lerner; J A Steitz
Journal:  Mol Cell Biol       Date:  1981-12       Impact factor: 4.272
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  84 in total

1.  Epstein-Barr virus small RNAs potentiate tumorigenicity of Burkitt lymphoma cells independently of an effect on apoptosis.

Authors:  I K Ruf; P W Rhyne; C Yang; J L Cleveland; J T Sample
Journal:  J Virol       Date:  2000-11       Impact factor: 5.103

2.  Localization of Epstein-Barr virus-encoded RNAs EBER-1 and EBER-2 in interphase and mitotic Burkitt lymphoma cells.

Authors:  M Schwemmle; M J Clemens; K Hilse; K Pfeifer; H Tröster; W E Müller; M Bachmann
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-01       Impact factor: 11.205

3.  Expression of Epstein-Barr virus genes and of lymphocyte activation molecules in undifferentiated nasopharyngeal carcinomas.

Authors:  G Niedobitek; L S Young; C K Sam; L Brooks; U Prasad; A B Rickinson
Journal:  Am J Pathol       Date:  1992-04       Impact factor: 4.307

Review 4.  Noncoding RNPs of viral origin.

Authors:  Joan Steitz; Sumit Borah; Demian Cazalla; Victor Fok; Robin Lytle; Rachel Mitton-Fry; Kasandra Riley; Tasleem Samji
Journal:  Cold Spring Harb Perspect Biol       Date:  2011-03-01       Impact factor: 10.005

Review 5.  Molecular basis for Epstein-Barr virus induced pathogenesis and disease.

Authors:  C Sample; E Kieff
Journal:  Springer Semin Immunopathol       Date:  1991

6.  Binding of Epstein-Barr virus small RNA EBER-1 to the double-stranded RNA-activated protein kinase DAI.

Authors:  P A Clarke; M Schwemmle; J Schickinger; K Hilse; M J Clemens
Journal:  Nucleic Acids Res       Date:  1991-01-25       Impact factor: 16.971

7.  Absence of Epstein-Barr virus in testicular germ cell tumours: a study of 21 cases using in situ hybridisation.

Authors:  N J Trendell-Smith; A Agathanggelou; H Herbst; C M Collins; N Rooney; G Niedobitek
Journal:  Clin Mol Pathol       Date:  1995-04

8.  Detection of Eber-1 RNA in primary brain lymphomas in immunocompetent and immunocompromised patients.

Authors:  R Bashir; B McManus; C Cunningham; D Weisenburger; F Hochberg
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

9.  Mature T/NK-cell lymphoproliferative disease and Epstein-Barr virus infection are more frequent in patients with rheumatoid arthritis treated with methotrexate.

Authors:  Seiji Kondo; Kazuki Tanimoto; Kozue Yamada; Goichi Yoshimoto; Eiichi Suematsu; Tomoaki Fujisaki; Yumi Oshiro; Kazuo Tamura; Morishige Takeshita; Seiichi Okamura
Journal:  Virchows Arch       Date:  2013-03-14       Impact factor: 4.064

Review 10.  Connivance, Complicity, or Collusion? The Role of Noncoding RNAs in Promoting Gammaherpesvirus Tumorigenesis.

Authors:  Whitney L Bullard; Erik K Flemington; Rolf Renne; Scott A Tibbetts
Journal:  Trends Cancer       Date:  2018-10-10
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