| Literature DB >> 30237953 |
Jie Liu1, Yujia Jiang1, Tianpeng Chen1, Weiliang Dong1,2, Wenming Zhang1,2, Jiangfeng Ma1,2, Min Jiang1,2, Fengxue Xin1,2.
Abstract
The genome of a wild-type solventogenic Clostridium sp. strain LJ4 that could directly convert undetoxified lignocellulosic hydrolysate to butanol and tolerate high concentration of furan and phenolic derivates occurring in the lignocellulosic hydrolysate is described. 16S rDNA gene sequencing and analysis indicated that it is closely related to Clostridium acetobutylicum. The genome size of strain LJ4 is 3.90 Mp, which has a G + C content of 30.72% and encodes 2711 proteins. It also has one 0.19 Mp plasmid with 181 predicted encoding proteins. Alcohol dehydrogenases (ADs) and a nicotinamide adenine dinucleotide phosphate (NADPH)-dependent flavin mononucleotide (FMN) reductase were identified, which may play key roles in inhibitors' resistance in lignocellulosic hydrolysate.Entities:
Keywords: Alcohol dehydrogenases; Clostridium; Draft genome sequencing; Furan and phenolic derivates; NADPH-dependent FMN reductase
Year: 2018 PMID： 30237953 PMCID： PMC6138001 DOI： 10.1007/s13205-018-1430-9
Source DB: PubMed Journal: 3 Biotech ISSN： 2190-5738 Impact factor: 2.406