| Literature DB >> 30235459 |
Kamila Zduńska, Agnieszka Dana, Anna Kolodziejczak, Helena Rotsztejn.
Abstract
Ferulic acid has low toxicity and possesses many physiological functions (anti-inflammatory, antioxidant, antimicrobial activity, anticancer, and antidiabetic effect). It has been widely used in the pharmaceutical, food, and cosmetics industry. Ferulic acid is a free radical scavenger, but also an inhibitor of enzymes that catalyze free radical generation and an enhancer of scavenger enzyme activity. Ferulic acid has a protective role for the main skin structures: keratinocytes, fibroblasts, collagen, elastin. It inhibits melanogenesis, enhances angiogenesis, and accelerates wound healing. It is widely applied in skin care formulations as a photoprotective agent, delayer of skin photoaging processes, and brightening component. Nonetheless, its use is limited by its tendency to be rapidly oxidized.Entities:
Keywords: Ferulic acid antioxidant; Photoaging
Mesh:
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Year: 2018 PMID: 30235459 DOI: 10.1159/000491755
Source DB: PubMed Journal: Skin Pharmacol Physiol ISSN: 1660-5527 Impact factor: 3.479