Literature DB >> 30233096

Direct-to-Consumer Genomics: Harmful or Empowering?: It is important to stress that genetic risk is not the same as genetic destiny.

Joel C Eissenberg1.   

Abstract

The price of whole-genome sequencing is now within the budget of the average American consumer. This has resulted in the commercialization of genome sequencing for a variety of applications, including health-related risk assessment. Direct-to-consumer marketing of personal DNA sequence information uncouples the generation of personal health-related data from the physician-patient relationship. Here, I discuss the status of consumer genomics and the current and potential concerns about bypassing physicians in the analysis and interpretation of personal genomic information and subsequent health care decision-making.

Entities:  

Year:  2017        PMID: 30233096      PMCID: PMC6143574     

Source DB:  PubMed          Journal:  Mo Med        ISSN: 0026-6620


  12 in total

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Journal:  J Community Genet       Date:  2012-04-05

Review 2.  Autonomy, paternalism, and justice: ethical priorities in public health.

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Journal:  Am J Public Health       Date:  2007-11-29       Impact factor: 9.308

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Authors:  Suzanne M Mahon
Journal:  J Oncol Pract       Date:  2012-07       Impact factor: 3.840

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Authors:  Robert C Green; Nita A Farahany
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Review 5.  To know or not to know: a review of behaviour and suicidal ideation in preclinical Huntington's disease.

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6.  Disclosure of APOE genotype for risk of Alzheimer's disease.

Authors:  Robert C Green; J Scott Roberts; L Adrienne Cupples; Norman R Relkin; Peter J Whitehouse; Tamsen Brown; Susan LaRusse Eckert; Melissa Butson; A Dessa Sadovnick; Kimberly A Quaid; Clara Chen; Robert Cook-Deegan; Lindsay A Farrer
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7.  A systematic survey of loss-of-function variants in human protein-coding genes.

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Authors:  Deanna Alexis Carere; Tyler VanderWeele; Tanya A Moreno; Joanna L Mountain; J Scott Roberts; Peter Kraft; Robert C Green
Journal:  BMC Med Genomics       Date:  2015-10-15       Impact factor: 3.063

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Authors:  Rachel R J Kalf; Raluca Mihaescu; Suman Kundu; Peter de Knijff; Robert C Green; A Cecile J W Janssens
Journal:  Genet Med       Date:  2013-06-27       Impact factor: 8.822

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  5 in total

1.  Direct-to-consumer personal genomic tests need better regulation.

Authors:  Osman Moneer; Jennifer E Miller; Nilay D Shah; Joseph S Ross
Journal:  Nat Med       Date:  2021-05-20       Impact factor: 53.440

2.  Genomic Database Grows.

Authors:  Joel C Eissenberg
Journal:  Mo Med       Date:  2017 May-Jun

3.  Journal of Translational Medicine advances in Translational Genomics and Genetics Era.

Authors:  Wei Liu
Journal:  J Transl Med       Date:  2019-04-25       Impact factor: 5.531

4.  Physician Experience with Direct-To-Consumer Genetic Testing in Kaiser Permanente.

Authors:  M Cabell Jonas; Pim Suwannarat; Andrea Burnett-Hartman; Nikki Carroll; Michelle Turner; Kristen Janes; Christine Truong; Erica Blum-Barnett; Nazneen Aziz; Elizabeth A McGlynn
Journal:  J Pers Med       Date:  2019-11-01

Review 5.  Privacy considerations for sharing genomics data.

Authors:  Marie Oestreich; Dingfan Chen; Joachim L Schultze; Mario Fritz; Matthias Becker
Journal:  EXCLI J       Date:  2021-07-16       Impact factor: 4.068

  5 in total

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