| Literature DB >> 30231040 |
Ilona Fridman1, Joanna L Hart2,3,4,5,6,7, Kuldeep N Yadav2,3,4,5, E Tory Higgins1,8.
Abstract
Patients engaging in shared decision making must weigh the likelihood of positive and negative outcomes and deal with uncertainty and negative emotions in the situations where desirable options might not be available. The use of "nudges," or communication techniques that influence patients' choices in a predictable direction, may assist patients in making complex decisions. However, nudging patients may be perceived as inappropriate influence on patients' choices. We sought to determine whether key stakeholders, physicians, and laypersons without clinical training consider the use of nudges to be ethical and appropriate in medical decision making. Eighty-nine resident-physicians and 336 Mechanical-Turk workers (i.e., non-clinicians) evaluated two hypothetical preference-sensitive situations, in which a patient with advanced cancer chooses between chemotherapy and hospice care. We varied the following: (1) whether or not the patient's decision was influenced by a mistaken judgment (i.e., decision-making bias) and (2) whether or not the physician used a nudge. Each participant reported the extent to which the communication was ethical, appropriate, and desirable. Both physicians and non-clinicians considered using nudges more positively than not using them, regardless of an initial decision-making bias in patients' considerations. Decomposing this effect, we found that physicians viewed the nudge that endorsed hospice care more favorably than the nudge that endorsed chemotherapy, while non-clinicians viewed the nudge that endorsed chemotherapy more favorably than the nudge that endorsed hospice care. We discuss implications and propose exploring further physicians' and patients' differences in the perception of nudges; the differences may suggest limitations for using nudges in medical decisions.Entities:
Mesh:
Substances:
Year: 2018 PMID: 30231040 PMCID: PMC6145510 DOI: 10.1371/journal.pone.0202874
Source DB: PubMed Journal: PLoS One ISSN: 1932-6203 Impact factor: 3.240
Decision-making vignettes and manipulations.
| Decision-making vignette 1: | Decision-making vignette 2: | |
|---|---|---|
| Patient’s initial treatment choice | Chemotherapy | Hospice care |
| Patient’s bias (manipulation 1) | Overestimating positive outcomes: the patient mistakenly believes that he may live much longer or be cured of the cancer | Availability bias: the patients’ friend told her that when chemotherapy passes through veins, it causes terrible pain |
| Physician’s rationale | Chemotherapy is not curative and will do more harm than good for him. It will cause tiredness and pain and increase the risk of infection. | Chemotherapy would likely benefit the patient by prolonging her life up to 18–24 months. |
| Physician’s recommendation | Hospice care | Chemotherapy |
| Decision-making nudge | Framing: if the patient is focused on avoiding losing a chance for a cure by choosing chemotherapy, the physician could re-focus the patient's attention. To do so, he should mention gains the patient could achieve by choosing comfort care instead of chemotherapy (i.e. more meaningful time with his family and friends). Prior research suggests that this decision-making approach will make it more likely that the patient will choose comfort-oriented care for advanced cancer. | Social comparison: The physician could inform the patient that a recent patient in a similar situation received the same treatment. It shrunk her cancer and allowed her to live longer than she would have been expected to live without any treatment. Additionally, medications helped manage the side effects of chemotherapy. Prior research has shown that this approach will make it more likely that the patient will choose chemotherapy. |
| Physician decision about using nudge (manipulation 2) | The physician decides to | The physician decides to |
* randomized: presented only for a half of the participants
Dependent variables.
| Variable | Item | Cronbach’ alfa non-clinicians | Cronbach’ alfa Physicians |
|---|---|---|---|
| Ethics | The physician's communication was ethical. | — | — |
| Desirability | I would prefer my physician to use this approach in a similar situation (non-clinicians) | — | — |
| Acceptability | The physician's behavior was unacceptable. (Reversed) | — | — |
| Effectiveness | The physician did the best she/he could for this patient. | .74 /81 | .62/75 |
| Autonomy | The physician respected the autonomy (freedom of choice) of the patient in this communication. | .65/.57 | .65/.68 |
| Benevolence | The physician acted in the best interests of the patient. | — | — |
| Respect to Patient | The physician treated the patient with dignity and respect | — | — |
| Trust | The patient will trust in his/her physician after this communication. | — | — |
Demographic characteristics of physicians and non-clinicians.
| Non-clinicians (n = 336) | Physicians (n = 89) | |
|---|---|---|
| Age in years, mean (SD) | 32 (10) | 30 (2) |
| Gender: Female | 64% | 38% |
| Race: White | 78% | 62% |
Physicians specialty.
| Residency | n | % |
|---|---|---|
| Anesthesiology | 14 | 15.9 |
| Dermatology | 3 | 3.4 |
| Emergency Medicine | 10 | 11.4 |
| Family Medicine & Community Health | 4 | 4.5 |
| General Surgery | 1 | 1.1 |
| Internal Medicine | 31 | 35.2 |
| Neurology | 3 | 3.4 |
| Obstetrics and Gynecology | 4 | 4.5 |
| Ophthalmology | 2 | 2.3 |
| Orthopedics | 5 | 5.7 |
| Otolaryngology | 1 | 1.1 |
| Physical Medicine and Rehabilitation | 5 | 5.7 |
| Psychiatry | 1 | 1.1 |
| Radiation Oncology | 2 | 2.3 |
| Urology | 2 | 2.3 |
| Unknown | 1 | 1.1 |
| Total | 89 | 100 |
Non-clinicians’ evaluations of communications by domain.
| Advice for Hospice Care | Advice for Chemotherapy | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No Nudge, | Nudge, | Comparison | No Nudge, | Nudge, | Comparison | |||||
| No Bias | Bias | No Bias | Bias | F, and p-value | No Bias | Bias | No Bias | Bias | F, and p-value | |
| Ethics | 4.47 | 5.30 | 5.63 | 27.26, | 4.53 | 5.65 | 5.68 | 75.66, | ||
| Desirability | 3.57 | 5.10 | 5.40 | 70.32, | 3.34 | 5.39 | 5.53 | 161.34, | ||
| Acceptability | 4.49 | 5.38 | 5.52 | 21.57, | 4.56 | 5.68 | 5.81 | 65.11, | ||
| Effectiveness | 3.58 | 4.88 | 4.88 | 72.84, | 3.51 | 5.32 | 5.34 | 224.36, | ||
| 4.37 | 4.58 | 4.66 | 0.52, | 4.63 | 5.09 | 5.20 | 11.64, | |||
| Benevolence | 3.94 | 5.46 | 5.67 | 75.09, | 3.74 | 5.71 | 5.84 | 190.77, | ||
| Respect to Patient | 4.49 | 5.30 | 5.41 | 17.15, | 4.48 | 5.58 | 5.65 | 63.21, | ||
| Trust | 4.41 | 4.99 | 4.84 | 7.20, | 4.10 | 5.49 | 5.49 | 87.40, | ||
The baseline group is bolded, in this group participants observed communication without nudge and without bias.
Physicians’ evaluations of communications by domain.
| Advice for Hospice Care | Advice for Chemotherapy | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No Nudge, | Nudge, | Comparison | No Nudge, | Nudge, | Comparison | |||||
| No Bias | Bias | No Bias | Bias | F, and p-value | No Bias | Bias | No Bias | Bias | F, and p-value | |
| Ethics | 4.30 | 6.09 | 6.00 | 39.75, | 3.96 | 5.23 | 5.50 | 15.63, | ||
| Desirability | 2.83 | 5.87 | 5.39 | 54.43, | 2.96 | 4.45 | 4.73 | 13.33, | ||
| Acceptability | 4.70 | 6.09 | 6.13 | 22.95, | 4.04 | 5.50 | 5.41 | 9.27, | ||
| Effectiveness | 2.78 | 5.15 | 4.83 | 102.75, | 2.83 | 4.55 | 4.73 | 31.10, | ||
| Autonomy | 4.54 | 5.19 | 5.08 | 7.04, | 4.39 | 4.32 | 4.89 | 0.03, | ||
| Benevolence | 3.65 | 6.13 | 5.48 | 47.11, | 3.30 | 5.05 | 5.55 | 28.62, | ||
| Respect to Patient | 4.17 | 6.09 | 5.74 | 46.53, | 4.13 | 5.32 | 5.27 | 9.77, | ||
| Trust | 4.17 | 5.57 | 5.09 | 10.41, | 4.26 | 5.27 | 5.32 | 9.50, | ||
The baseline group is bolded, in this group participants observed communication without nudge and without bias.
* Patients evaluated approach as more acceptable and trustworthy when bias was not present, independently if nudge was present or absent.
Comparing physicians’ and patients’ evaluations of the communication, in which hospice care was endorsed.
| Hospice is endorsed: Nudge | Chemotherapy is endorsed: Nudge | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Non-clinicians, | Physicians, | Non-clinicians vs. physicians | Non-clinicians, | Physicians, | Non-clinicians vs. physicians | |||||
| No Bias | Bias | No Bias | Bias | F, and p-value | No Bias | Bias | No Bias | Bias | F, and p-value | |
| Ethics | 5.30 | 5.63 | 6.09 | 6.00 | 10.10, | 5.65 | 5.68 | 5.23 | 5.50 | 2.84, |
| Desirability | 5.10 | 5.40 | 5.87 | 5.39 | 2.91, | 5.39 | 5.53 | 4.45 | 4.73 | 13.61. |
| Acceptability | 5.38 | 5.52 | 6.09 | 6.13 | 8.52, | 5.68 | 5.81 | 5.50 | 5.41 | 1.52, |
| Effectiveness | 4.88 | 4.88 | 5.15 | 4.83 | 0.49, | 5.32 | 5.34 | 4.55 | 4.73 | 18.07, |
| 5.20 | 5.09 | 6.44, | 5.10 | 5.20 | 4.32 | 4.89 | 6.91, | |||
| Benevolence | 5.46 | 5.67 | 6.13 | 5.48 | 1.43, | 5.71 | 5.84 | 5.05 | 5.55 | 6.09, |
| Respect to Patient | 5.30 | 5.41 | 6.09 | 5.74 | 8.81, | 5.58 | 5.65 | 5.32 | 5.27 | 2.96, |
| Trust | 4.99 | 4.84 | 5.57 | 5.09 | 4.37, | 5.49 | 5.49 | 5.27 | 5.32 | 1.14, |